P2X7 Receptor Inhibition Interrupts the Progression of Seizures in Immature Rats and Reduces Hippocampal Damage.

CONCLUSIONS: These results suggest P2X7 receptor antagonists may be suitable as frontline or adjunctive treatments of pediatric status epilepticus or other early-life seizures, particularly when associated with brain damage. PMID: 24750893 [PubMed - as supplied by publisher]

http://www.ncbi.nlm.nih.gov/pubmed/24750893?dopt=Abstract

Source: CNS Neuroscience and Therapeutics - April 21, 2014 Category: Neuroscience Authors: Mesuret G, Engel T, Hessel EV, Sanz-Rodriguez A, Jimenez-Pacheco A, Miras-Portugal MT, Diaz-Hernandez M, Henshall DC Tags: CNS Neurosci Ther Source Type: research

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