Antimicrobial peptide exposure selects for Staphylococcus aureus resistance to human defence peptides
Conclusions
These findings suggest that therapeutic use of AMPs could select for virulent mutants with cross-resistance to human innate immunity as well as antibiotic therapy. Thus, therapeutic use of AMPs and the implications of cross-resistance need to be carefully monitored and evaluated.
Source: Journal of Antimicrobial Chemotherapy - Category: Microbiology Authors: Kubicek-Sutherland, J. Z., Lofton, H., Vestergaard, M., Hjort, K., Ingmer, H., Andersson, D. I. Tags: Original research Source Type: research
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