Avoiding over-the-counter heartburn meds could save cancer patients' lives

(University of Alberta Faculty of Medicine&Dentistry) Something as seemingly harmless as a heartburn pill could lead cancer patients to take a turn for the worse. A University of Alberta study published in the journal JAMA Oncology discovered that proton pump inhibitors, which are very common medications for heartburn and gastrointestinal bleeding, decrease effects of capecitabine, a type of chemotherapy usually prescribed to gastric cancer patients.
Source: EurekAlert! - Medicine and Health - Category: Global & Universal Source Type: news

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A growing link—what is the role of height in cancer risk?A growing link—what is the role of height in cancer risk?, Published online: 19 February 2019; doi:10.1038/s41416-018-0370-9A growing link—what is the role of height in cancer risk?
Source: British Journal of Cancer - Category: Cancer & Oncology Authors: Source Type: research
Adult height in relation to risk of cancer in a cohort of 22,809,722 Korean adults, Published online: 19 February 2019; doi:10.1038/s41416-018-0371-8Adult height in relation to risk of cancer in a cohort of 22,809,722 Korean adults
Source: British Journal of Cancer - Category: Cancer & Oncology Authors: Source Type: research
Publication date: Available online 18 February 2019Source: Research in Veterinary ScienceAuthor(s): Hong-Xia Wang, Xi-Lan Lu, Wen-Jie Huang, Jian-Min ZhangAbstractThe aim of this study was to investigate the role of pyroptosis in the cryopreservation and transplantation of mouse ovarian tissues; the effects of pyroptosis inhibitior on the ovarian graft function were also explored. ICR (institute of cancer research) mice were randomly divided into control group and experimental groups (n = 10 per group). The experimental groups included fresh graft group (autograft), cryopreserved graft group (cryopreservation + aut...
Source: Research in Veterinary Science - Category: Veterinary Research Source Type: research
(MedPage Today) -- Also, how to prevent unplanned hospitalization for cancer patients
Source: MedPage Today Public Health - Category: American Health Source Type: news
Lupron (leuprolide acetate) is a type of hormone therapy for people with prostate cancer. Lupron is an injection drug, and doctors often prescribe it in combination with radiation therapy or surgery. As it lowers a person ’s testosterone levels, Lupron can cause a range of side effects. Learn more here.
Source: Health News from Medical News Today - Category: Consumer Health News Tags: Prostate / Prostate Cancer Source Type: news
Org. Biomol. Chem., 2019, Accepted Manuscript DOI: 10.1039/C9OB00318E, PaperJosu é Carvalho, Jéssica Lopes Nunes, Ana Catarina Lopes, Maria Paula Cabral Campello, António Rocha Paulo, João António Queiroz, Carla Cruz DNA aptamers represent a way to target cancer cells at a molecular level and continue to be developed with a view to improve treatment and imaging in cancer medicine. AT11-L0,... The content of this RSS Feed (c) The Royal Society of Chemistry
Source: RSC - Organic and Biomolecular Chemistry - Category: Molecular Biology Authors: Source Type: research
Cancer is a complex disease which involves abnormalities of multiple cellular pathways. Current chemotherapeutic drugs are mainly designed to target the DNA and cell division. Therefore, in the present study, we have synthesized a new series of 1,2,3-triazolo-naphthalimide/phthalimide conjugates and evaluated their in vitro cytotoxicity against selected human cancer cells. Among the tested compounds, one of them displayed notable cytotoxic activity against A549 lung cancer cells with an IC50 (half maximal inhibitory concentration) value of 7.6 ± 0.78 µM. To determine the effect of this compound on cell viabili...
Source: Journal of the Brazilian Chemical Society - Category: Chemistry Source Type: research
Conclusion This larger set of observational data finds that PPI drugs are associated with an increase in the risk of early death compared with either H2 blockers or no acid suppression drugs. This was the case for participants both with and without gastrointestinal problems. It also appears as though the longer the PPIs drugs are taken, the greater the risk of death. Considering that these drugs are widely used in the UK, these findings may cause concern. But the research has a number of important limitations: The study was conducted in a population of mostly white, older US male veterans, which might limit the abi...
Source: NHS News Feed - Category: Consumer Health News Tags: Medication Source Type: news
In 1982, two Australian scientists discovered that a certain bacterium, Helicobacter pylori, was a common cause of persistent stomach inflammation and stomach ulcers. This realization revolutionized ulcer treatment. While fairly common, this infection usually causes no symptoms, but it can sometimes lead to ulcers in the stomach or the very first part of the small intestine (duodenum), and to certain types of stomach cancer. There is also evidence linking H. pylori infection to other conditions like iron-deficiency anemia and vitamin B12 deficiency. The bacteria are thought to spread through contaminated water, vomit, or f...
Source: Harvard Health Blog - Category: Consumer Health News Authors: Tags: Digestive Disorders Health Infectious diseases Tests and procedures Source Type: blogs
The post I still don’t think it is necessary! – Sian’s story appeared first on Hysterectomy Association. Well, as you will see, the title of my story isn’t strictly true, but my journey started when I went to my GP with slight menopausal bleeding. It took me a few days to decide whether it was bleeding or just slightly coloured discharge, however, she told me that they always refer anyone over 60 with post menopausal bleeding to the aptly named ‘post menopausal bleeding clinic’! I was out enjoying a meal with friends, when I received a phone call from the clinic inviting me in for a cons...
Source: The Hysterectomy Association - Category: OBGYN Authors: Tags: Your Stories cancer Source Type: news
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