Cochrane Priority Reviews List: December 2016 Update

Cochrane-wide prioritisation remains an important project, with over 140 priority reviews or updates have been published since it began in January 2015.The December 2016 revision of the Cochrane Priority Reviews List includes new titles from the Cochrane Airways, Anaesthesia, Dementia&Cognitive Improvement, ENT, Epilepsy, Gynaecological, Neuro-oncology and Orphan Cancers, Gynaecology&Fertility, Haematological Malignancies, Heart, Incontinence, Kidney&Transplant, Lung Cancer, Neuromuscular Disease, Oral Health, Skin, Stroke, and Urology Groups.The following titles on the list are open to new authors:Long-acting beta2-agonists and long-acting muscarinic antagonists in a combined inhaler versus either agent alone or placebo for chronic obstructive pulmonary diseaseProstacyclin for pulmonary hypertension in adultsWeight loss intervention through lifestyle modification or pharmacotherapy for obstructive sleep apnoea in adultsOutpatient treatment of diverticulitisPrevention of recurrent diverticulitisProphylactic antibiotics for preventing recurrent symptomatic episodes of acute diverticulitisAntibiotics for trachomaBiomarkers for predicting outcomes in endometrial cancerDiagnostic test accuracy of sentinel LN node sampling in endometrial cancerInterventions to improve insulin resistance for the prevention of endometrial cancerInterventions to promote early referral for women with symptoms of endometrial cancerImmunomodulatory treatment for amyotrophic lateral sclerosis...
Source: Cochrane News and Events - Category: Information Technology Authors: Source Type: news

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Authors: Lee HJ, Han YM, An JM, Kang EA, Park YJ, Cha JY, Hahm KB Abstract INTRODUCTION: Although inflammation is defensive and healing process that maintains organ homeostasis, unresolved inflammation can lead to diseases. Polyunsaturated fatty acids (PUFAs), especially n-6 PUFAs abundant in Western diet, are precursors of pro-inflammatory mediators, whereas n-3 PUFAs possess anti-inflammatory properties. Therefore, interest in the cancer-preventive effect of n-3 PUFAs is increasing. Areas covered: We have observed significant reductions of gastrointestinal (GI) tumorigenesis in the Fat-1 transgenic mouse as evide...
Source: Expert Review of Anticancer Therapy - Category: Cancer & Oncology Tags: Expert Rev Anticancer Ther Source Type: research
A new study suggests that exposure to large amounts of air pollution may be associated with a 40% heightened risk of dementia. The study, conducted in London, adds to a growing body of evidence that there could be a link between dirty air and dementia diagnoses.
Source: CNN.com - Health - Category: Consumer Health News Source Type: news
(MedPage Today) -- London study finds 40% increased risk among adults living with poorer air quality
Source: MedPage Today Psychiatry - Category: Psychiatry Source Type: news
Epileptic seizures often follow a circadian rhythm, which may eventually help guide therapy, researchers say.Medscape Medical News
Source: Medscape Medical News Headlines - Category: Consumer Health News Tags: Neurology & Neurosurgery News Source Type: news
was established in 2004 and consents patients in Wales, UK with a known or suspected cancer diagnosis to donate biosamples for future research. The resource is open access to all researchers working in cancer research, regardless of geographic location or employment sector. To December 2017, just over 13,500 patients have donated samples across a variety of tumour types. Tumour and adjacent normal tissue and blood samples are routinely collected, stored and processed to standardised protocols. Bespoke collections for unique samples such as urine or ascites are also available. Pathology data, clinical data including treatm...
Source: Open Journal of Bioresources - Category: Biotechnology Source Type: research
Type 2 diabetes prevents the body from responding to insulin correctly, leading to high levels of blood sugar. Some people require insulin injections, but others can manage the condition with oral or other injectable medications. Learn more here.
Source: Health News from Medical News Today - Category: Consumer Health News Tags: Diabetes Type 2 Source Type: news
Authors: Czemerska M, Robak T, Wierzbowska A Abstract INTRODUCTION: Acute myeloid leukemia (AML) remains a poor prognosis hematological malignancy. The introduction of aggressive chemotherapy with allogeneic stem cell transplantation has resulted in improved clinical outcomes in younger patients. However, the treatment results in unfit elderly AML population remain disappointing. New strategies should be introduced to improve the prognosis in this group of patients. Areas covered: This review presents and discusses the mechanism of action, safety and efficacy of sapacitabine in AML patients. Expert opinion: Sapacit...
Source: Expert Opinion on Pharmacotherapy - Category: Drugs & Pharmacology Tags: Expert Opin Pharmacother Source Type: research
Authors: Daniels LM, Kufel WD Abstract INTRODUCTION: Clostridium difficile infection (CDI) has become a significant healthcare-associated infection and is strongly associated with antibiotic use. Practice guidelines have recently been revised incorporating updated recommendations for diagnosis, treatment, and prevention. Areas Covered: This review discusses updated aspects of CDI management. New and emerging pharmacologic options for treatment and prevention are reviewed. Expert opinion: Metronidazole is associated with lower rates of treatment success compared to vancomycin and should no longer be used as primary ...
Source: Expert Opinion on Pharmacotherapy - Category: Drugs & Pharmacology Tags: Expert Opin Pharmacother Source Type: research
(Reuters Health) - Postmenopausal women who experience problems like vaginal dryness, painful intercourse or urinary incontinence may want to see a gynecologist instead of a primary care provider for help, a recent study suggests.
Source: Reuters: Health - Category: Consumer Health News Tags: healthNews Source Type: news
High blood pressure, which is a risk factor for stroke and heart disease, claimed almost 8 million lives around the world in 2015 alone, the researchers noted.
Source: WebMD Health - Category: Consumer Health News Source Type: news
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