Long-term painkiller use 'linked to hearing loss in women'
Conclusion Many people use medicines like paracetamol or ibuprofen for aches and pains. There's no suggestion from this study that occasional use to manage a headache or muscle strain is harmful. But the study is a reminder that regular use – defined by the researchers as two days or more a week – could have health consequences over time. However, this study has some limitations. As a cohort study, it can't prove cause and effect between paracetamol and NSAIDs and hearing loss. And it mainly included white women, all in the US, so we don't know if the results apply to other groups. Also, the increased risk was small – as there's no information about some factors that can also affect hearing, such as exposure to loud noise, it's possible unmeasured confounding factors might have explained the link. As hearing loss was not measured by hearing tests but just by asking people if they'd had hearing problems, it is subject to further diagnostic uncertainty. Overall, however, this study adds to previous evidence that the regular use of paracetamol and NSAID medicines could be a factor in some cases of hearing loss. It makes sense to limit your use of these drugs to when they're needed. If you find you have to take painkillers on several days a week, it's probably a good idea to talk to your doctor about what's causing the pain and whether there are better ways to manage it. Hearing loss is common as people get older. There are ways to protect your hearing&n...
Conclusions:: The association between plasma lipids and cognition, the mechanism of the influence of plasma lipids on cognitive function, and the association between statins and cognitive function are complex issues and currently not fully understood. Future research aimed at identifying the mechanisms that underlie the effects of plasma lipids and statins on cognition will not only provide important insight into the causes and interdependencies of cognitive impairment and dementia, but also inspire novel strategies for treating and preventing these cognitive disorders. PMID: 29451153 [PubMed - in process]
Abstract Background: Most studies on enhanced recovery after surgery (ERAS) for gastric cancer exclude patients who received neoadjuvant chemotherapy. Here, we aimed to evaluate whether patients who received neoadjuvant chemotherapy can be enrolled into the ERAS program for locally advanced gastric cancer. Methods: From April 2015 to July 2017, 114 patients who received neoadjuvant chemotherapy for locally advanced gastric cancer were randomized into ERAS and standard care (SC) groups. Postoperative length of stay, complications, bowel function, and nutritional status were recorded. Results:: The postope...
Conclusions: The analysis of different payment modes toward the medical economic characteristics based on Gamma model is basically rational. Medical payment modes are having certain influence toward the hospitalization expenses of cervical cancer patients in an extent, as drug costs, treatment costs, and examination costs appear to be the main causes. PMID: 29451142 [PubMed - in process]
Abstract Background: Obesity induces dyslipidemia, hypertension, glucose intolerance, and inflammatory state, which results in atherogenic processes, diabetes, and cardiovascular disease. We usually use body composition indices, such as body mass index (BMI), body fat percentage (BFP), waist circumference-height ratio (WHtR), and waist-hip ratio (WHR) to reflect the obesity. The aim of this large population-based cross-sectional study was to investigate the associations between body composition indices and metabolic parameters in Chinese adults. Methods: A total of 12,018 Chinese adults were included. Body co...
https://www.usnews.com/news/best-states/missouri/articles/2018-02-16/doctor-said-it-was-cancer-it-wasnt-but-news-came-too-late Interesting article.
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This study assessed and compared the resource requirement of 3 adaptive strategies.
International brachytherapy consortiums are advocating for the incorporation of magnetic resonance imaging (MRI) into the cervical brachytherapy process as a standard-of-care. Although some evaluations have been performed to quantify the effect on procedural time, little is known about the views and experiences of key stakeholders during the transition from CT to MR-guided brachytherapy. This qualitative research project explored insights from key stakeholders related to a change in the gynaecological brachytherapy process.
Radiation review is a weekly clinic in the radiotherapy treatment (RT) care trajectory. It is an opportunity for patients undergoing RT to discuss emergent health issues with their care team. Recently, there was an opportunity to leverage technology to improve the arrival process of patients to this clinic and communication amongst the care team.
Healthcare leaders are brought together into teams to accomplish complex tasks, ranging from clinical operations to strategic planning. Frequently, little consideration is given to the team members' different strengths and styles, or how those differences may impact on the effectiveness of the leadership team. The purpose of this initiative was to improve the effectiveness of a Radiation Therapy (RT) Leadership Team at a large, academic cancer centre using evidence-based team strengthening techniques.
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