Endothelial repair in stented arteries is accelerated by inhibition of Rho-associated protein kinase

Conclusions
Stent struts delay endothelial repair by generating localized bidirectional flow which traps migrating EC. ROCK inhibitors accelerate endothelial repair of stented arteries by enhancing EC polarity and migration through regions of bidirectional flow.

Source: Cardiovascular Research - December 14, 2016 Category: Cardiology Authors: Hsiao, S. T., Spencer, T., Boldock, L., Prosseda, S. D., Xanthis, I., Tovar-Lopez, F. J., Van Beusekom, H. M. M., Khamis, R. Y., Foin, N., Bowden, N., Hussain, A., Rothman, A., Ridger, V., Halliday, I., Perrault, C., Gunn, J., Evans, P. C. Tags: Vascular biology Source Type: research