Magnetic resonance imaging of infarct-induced canonical wingless/integrated (Wnt)/{beta}-catenin/T-cell factor pathway activation, in vivo

Conclusions
The TCF/Lef promoter-hFTH construct is a novel and reliable MRI reporter gene for in vivo detection of the canonical Wnt/β-catenin/TCF activation state in response to cardiac injury and therapeutic interventions.

Source: Cardiovascular Research - December 14, 2016 Category: Cardiology Authors: Matteucci, M., Casieri, V., Gabisonia, K., Aquaro, G. D., Agostini, S., Pollio, G., Diamanti, D., Rossi, M., Travagli, M., Porcari, V., Recchia, F. A., Lionetti, V. Tags: Cardiac biology and remodelling Source Type: research