Optimization of the Radiation Management of High-Risk Prostate Cancer

Radiation and androgen-deprivation therapy (ADT) are mainstays of treatment for men with high-risk prostate cancer. High-risk disease is heterogeneous and subcategories of “favorable” high risk and very high risk can identify subgroups with particularly good or poor prognosis to help personalize treatment. Overall, randomized trials show that the combination of radiation and ADT improves survival when compared with either by itself. The optimum duration of ADT rem ains controversial, but for most healthy men with aggressive disease, approximately 2-3 years of ADT is well supported by the literature.
Source: Seminars in Radiation Oncology - Category: Cancer & Oncology Authors: Source Type: research