What Sofia Vergara's Case Reveals About IVF's Legal Gray Areas

Couples who create IVF embryos together should consider hiring lawyers before beginning the fertility treatment process, according to reproductive law experts. While unpleasant, much like a prenup, the process can help avoid a messy, complicated legal battle like the “custody” lawsuit against actress Sofia Vergara by her ex-fiancé, Nick Loeb. Few couples take this extra step before attempting IVF. But Vergara and Loeb’s case underscores the need for conscientious couples to prepare for every potential future scenario, no matter how unlikely, said San Diego-based surrogacy lawyer Stephanie Caballero.  Couples already sign consent forms that detail how an IVF lab should distribute embryos in cases of death, divorce and other scenarios, but those forms are an agreement between two parties: the couple and the IVF clinic, not between the partners themselves, explained Caballero, an executive board member of the American Society for Reproductive Medicine’s legal professional group.  Couples who want to guard against any future ambiguity should also hire individual lawyers to hammer out an agreement between themselves, she says. Caballero estimates that hiring lawyers for each partner would add $1,300 to $1,500 to the total cost of IVF, which averages $12,400.   “Would it cost you an extra $1,000 to hire a separate attorney? Yes. One would draft, and the other would review it with [you],” said Caballero, who is...
Source: Healthy Living - The Huffington Post - Category: Consumer Health News Source Type: news

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Publication date: Available online 17 October 2018Source: Respiratory Medicine Case ReportsAuthor(s): Saad Habib, Lazer Ezriel Leifer, Mohammed Azam, Abdul Hasan Siddiqui, Kartikeya Rajdev, Michel ChalhoubAbstractGiant Cell Carcinoma of the lung, a subtype of Sarcomatoid lung cancer is a poorly differentiated Non-Small-Cell Lung Cancer. GCCL has exceptionally aggressive characteristics, and its prognosis is much poorer than any other NSCLCs. Herein, we present a rare case of Giant Cell Carcinoma of lung treated successfully with surgical resection and adjuvant vinorelbine and cisplatin.A 48-year-old African American man wi...
Source: Respiratory Medicine Case Reports - Category: Respiratory Medicine Source Type: research
Authors: Fontana J, Zima M, Vetvicka V Abstract Numerous conditions, including cancer, diabetes, aging, and atherosclerosis, are thought to be associated with oxidative stress. Oxidative stress is defined as a persistent imbalance between oxidation and antioxidation, resulting in the damage of cellular macromolecules and is often considered to be involved in wide variety of human diseases. However, the current literature is very heterogeneous making it rather difficult to draw general conclusions. Often, different biomarkers have been used in different health problems. In addition, individual biomarkers are often m...
Source: Immunological Investigations - Category: Allergy & Immunology Tags: Immunol Invest Source Type: research
In conclusion, the Vγ9Vδ2 T cells activated by cancer cell lysate showed APC characteristics, and this may greatly increase interest in investigating their therapeutic potential in hematologic malignancies. Abbreviations: CML: chronic myeloid leukemia; APC: antigen-presenting cell; TCR: T cell receptor; MHC: major histocompatibility complex; N-BPs: nitrogen-containing bisphosphonates; IPP: isopentenyl pyrophosphate; PBMC: peripheral blood mononuclear cells; NKG2D: natural killer receptor group 2, member D; TRAIL: tumor necrosis factor-related apoptosis-inducing ligand. PMID: 30321079 [PubMed - as supplied by publisher]
Source: Immunological Investigations - Category: Allergy & Immunology Tags: Immunol Invest Source Type: research
Publication date: Available online 16 October 2018Source: NeuroImage: ClinicalAuthor(s): Xing Liu, Yiming Li, Zenghui Qian, Zhiyan Sun, Kaibin Xu, Kai Wang, Shuai Liu, Xing Fan, Shaowu Li, Zhong Zhang, Tao Jiang, Yinyan WangAbstractObjectiveThe aim of this study was to develop a radiomics signature for prediction of progression-free survival (PFS) in lower-grade gliomas and to investigate the genetic background behind the radiomics signature.MethodsIn this retrospective study, training (n = 216) and validation (n = 84) cohorts were collected from the Chinese Glioma Genome Atlas and the Cancer Genome Atlas, respecti...
Source: NeuroImage: Clinical - Category: Radiology Source Type: research
Authors: Papadia A, Gasparri ML, Wang J, Radan AP, Mueller MD Abstract The risk of lymph nodal metastases in endometrial cancer varies greatly according to the characteristics of the primary tumor. Surgical staging with a systematic lymphadenectomy in endometrial cancer is debated since three decades. On one hand, it provides important pathological information on the spread of the tumor allowing for an appropriate decision making on adjuvant treatment but on the other side it is characterized by a non negligible short and long term morbidity. In the past decades, various efforts have been made in the attempt to app...
Source: Minerva Ginecologica - Category: OBGYN Tags: Minerva Ginecol Source Type: research
Authors: Di Sarno R, Raffone A, Saccone G Abstract Different strategies have been adopted for prevention of spontaneous preterm birth, including use of progestogens. So far, five randomized trials have been published evaluating the efficacy of progestogens in women with PPROM, including a total of 425 partipants. All the five trials enrolled pregnant women with singleton pregnancies randomized between 20 and 34 weeks of gestation. In four trials women were randomized to either weekly intramuscular 250 mg 17α-hydroxyprogesterone-caproate or placebo, while Mirzaei et al. was a three arms trials in which women r...
Source: Minerva Ginecologica - Category: OBGYN Tags: Minerva Ginecol Source Type: research
Authors: Nasioudis D, Doulaveris G, Kanninen TT Abstract Hyperlipidemia is a known cause of atherosclerosis and directly contributes to the current epidemic in cardio-vascular disease. Pregnancy is typified by an increase in serum levels of total cholesterol and triglycerides pushed by the rise in estrogen, progesterone and lactogen. Mobilization of stored fat depots in late pregnancy may provide a reservoir of fatty acids for fetal growth and placental tissue steroid synthesis. This physiologic increase in lipids performs an essential role during pregnancy; however, elevated levels of lipids in predisposed women o...
Source: Minerva Ginecologica - Category: OBGYN Tags: Minerva Ginecol Source Type: research
CONCLUSIONS: This systematic review confirms the importance of HE4 in the diagnosis of epithelial ovarian cancer and its promising role in endometrial cancer (endometrioid hystology). PMID: 30318876 [PubMed - as supplied by publisher]
Source: Minerva Ginecologica - Category: OBGYN Tags: Minerva Ginecol Source Type: research
CONCLUSIONS: Management of pregnant women with cancer should be performed in specialized cancer centers and all cases should be discussed with a multidisciplinary approach. In the present review, we discuss the current recommendations for the management of pregnancies complicated by cancer and neonatal outcomes. PMID: 30318875 [PubMed - as supplied by publisher]
Source: Minerva Ginecologica - Category: OBGYN Tags: Minerva Ginecol Source Type: research
Authors: Seravalli V, Di Tommaso M, Petraglia F Abstract The main challenges in pregnancies affected by fetal growth restriction consist in identifying signs of disease progression and determining the appropriate timing of delivery. The risk of continuing the pregnancy must be balanced with the risk of prematurity, which depends on gestational age. To allow appropriate monitoring of the growth-restricted fetus, several surveillance tests are available. These include ultrasound Doppler velocimetry of feto-placental vessels, cardiotocography, and amniotic fluid evaluation. It is well known that the combination of tes...
Source: Minerva Ginecologica - Category: OBGYN Tags: Minerva Ginecol Source Type: research
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