Resistive Training and Molecular Regulators of Vascular-Metabolic Risk in Chronic Stroke

Peroxisome proliferator-activated receptor (PPAR)- γ coactivator (PGC-1α) gene and Sirtuin-1 (SIRT-1) respond to physiological stimuli and regulate insulin resistance. Inflammatory markers tumor necrosis factor-alpha (TNF-α), interleukin-6 (IL-6), C-reactive protein (CRP), and the soluble forms of intracellular adhesion molecule (sICAM-1) and vas cular CAM-1 (sVCAM-1) are associated with increased risk of diabetes and coronary heart disease. Resistive training (RT) reduces hyperinsulinemia and improves insulin action in chronic stroke.
Source: Journal of Stroke and Cerebrovascular Diseases - Category: Neurology Authors: Source Type: research