I Am Aggravated

My body is not cooperating. It keeps on bringing areas to my attention that are not cooperative, i.e., causing pain or other discomfort. I am not happy about this. I am already in PT for one area of the body that has expanded to a second area. I am going back to the knee doctor on Monday to talk about my formerly'good'knee which is causing way too many issues. My'bad'knee isn't going to be a good substitute for it.Also, my fatigue levels are not doing me any favors. I was so tired this afternoon that I didn't put away the groceries - except for the most perishable - and left them for my husband so I could go lie down.This does not make me happy. The roller coaster of cancer is bad enough, actually it probably the worst. But the fatigue and pain roller coaster isn't much better. I am not coping well. I am whining.And it snowed twice this week and we are due for more snow Monday and Wednesday of next week. This makes me less happy and more aggravated. Its time for my body to suck it up and get back in lie.
Source: Caroline's Breast Cancer Blog - Category: Cancer & Oncology Tags: aggravation knee pain whininess Source Type: blogs

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Rationale: Breast cancer is the most commonly diagnosed malignancies in females. The most common sites of metastasis are bone, lung, liver, and brain. Gastrointestinal and adrenal gland metastasis from breast cancer are rare. Simultaneous metastases are extremely rare. Therefore, it is critically important to choose proper examination and treatment since the rapid diagnosis and primary treatment can significantly affect the survival of patients. To the best of our knowledge, this was the first case of initial dual metastasis. Patient concerns: The patient had a history of left breast cancer, and she underwent left bre...
Source: Medicine - Category: Internal Medicine Tags: Research Article: Clinical Case Report Source Type: research
The headline in a main Finnish newspaper on 16 November announced: “Trust and interest for published science has increased in Finland”. I would have hypothesized that evidence-based knowledge was losing the game against the rush of non-scientific and commercial information – but I was wrong. A 3-year follow-up survey among the Finland population was clear on this. Could the growth in electronic and social media information actually be causing people to search for knowledge based on scientific facts? Forty-five years have passed since the publication of the first issue of the Scandinavian Journal of Work...
Source: Scandinavian Journal of Work, Environment and Health - Category: Occupational Health Tags: Editorial Source Type: research
It’s in the early morning of April 15th, 2030 that when looking at your smart mirror, the latter beeps a warning notification: that new mole on your chin should be checked by your dermatologist. That was to be expected. After all your genetic test revealed that you possess a mutation in the CDKN2A gene. But you also get the recommendation to have your esophagus and stomach checked as your connected smart scale registered a noticeable drop in weight and this mutation also carries an increased risk of gastrointestinal (GI) tract cancer. With such increased awareness and early stage diagnosis methods, will the cance...
Source: The Medical Futurist - Category: Information Technology Authors: Tags: Future of Medicine Personalized Medicine cancer digital health cancer treatment digital technology oncology cancer research cancer care digital health technologies Source Type: blogs
Conditions:   Anesthesia;   Analgesia;   Acute Pain;   Chronic Pain;   Pectoralis Nerve Block;   Erector Spine Plane Block;   Patient Controlled Analgesia Interventions:   Procedure: Pectoralis nerve block;   Procedure: Erector spine plane block;   Other: Control Sponsors:   Ondokuz Mayıs University;   CENGİZ KAYA (ckaya) Recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
TIME held its first TIME 100 Health Summit on Thursday aiming to define — and shape — the future of health care. The Summit, which is an offshoot of the magazine’s annual TIME 100 list of influential people, featured scientists, politicians and entertainers, such as former President Bill Clinton, former Vice President Al Gore, NIH Director Dr. Francis Collins, actress Selma Blair, NBA commissioner Adam Silver, comedian Tig Notaro and former Planned Parenthood President Dr. Leana Wen. The day included a range of interviews, panels and performances. Here are the biggest moments from the Summit. Former Vice ...
Source: TIME: Health - Category: Consumer Health News Authors: Tags: Uncategorized Comedy HealthSummit19 onetime Source Type: news
This study tested the hypothesis that vascular endothelial growth factor A and vascular endothelial growth factor receptor 2 contribute to bone cancer pain regulation associated with spinal central sensitization.Methods This study was performed on female rats using a metastatic breast cancer bone pain model. Nociceptive behaviors were evaluated by mechanical allodynia, thermal hyperalgesia, spontaneous pain, and CatWalk gait analysis. Expression levels were measured by real-time quantitative polymerase chain reaction, western blot, and immunofluorescence analysis. Excitatory synaptic transmission was detected by whole-cell...
Source: Anesthesiology - Category: Anesthesiology Source Type: research
Can we reduce the persistent, unbearable pain of losing a loved one to 15-20 voxels of brain activity in the nucleus accumbens (O'Connor et al., 2008)? No? Then what if I told you that unrelenting grief — and associated feelings of sheer panic, fear, terminal aloneness, and existential crisis — isn't “suffering”. It's actually rewarding!Well I'm here to tell you that it isn't.Looking back on apost from 2011, you never realize it's going to be you.1The top figure shows that activity in thenucleus accumbens was greater in response to grief-related words vs. neutral words in a group of 11 women with &l...
Source: The Neurocritic - Category: Neuroscience Authors: Source Type: blogs
We report a case of a 46-year-old woman with breast cancer complaining of back pain. 18F-NaF PET/CT images show focal increase uptake at facet joints of L5/S1 vertebrae and both knees joints, suggesting degenerative disease. There is normal variant 18F-NaF uptake noted in the ossification at the falx cerebri. Recognition of normal and abnormal extraosseous 18F-NaF uptake is important for correct interpretation to avoid unnecessary further investigations.
Source: Clinical Nuclear Medicine - Category: Nuclear Medicine Tags: Interesting Images Source Type: research
This study aimed to determine the impact of health symptoms on HRQoL in breast cancer patients up to 5  years after diagnosis.MethodsFemales surgically treated for early-stage breast cancer diagnosed between 2012 and 2016 (n = 876) were selected from the Netherlands Cancer Registry and invited for a survey about current health symptoms (‘Symptoms and Perceptions questionnaire’, SaP) and HRQoL (‘EORTC-QLQ-C30’). From the latter, functioning and global health were included. Mean scores were compared to norm p opulation scores (T test). Multivariable linear regression analyses were p...
Source: Breast Cancer Research and Treatment - Category: Cancer & Oncology Source Type: research
We present therapeutic options for bone metastasis using a multidisciplinary approach. Further, we describe future directions for bone metastasis management, focusing on novel bone-specific targeted therapies. PMID: 31456182 [PubMed - in process]
Source: Advances in Experimental Medicine and Biology - Category: Research Tags: Adv Exp Med Biol Source Type: research
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