Abnormal right ventricular-pulmonary artery coupling with exercise in heart failure with preserved ejection fraction

Conclusions In addition to limited LV reserve, patients with HFpEF display impaired RV reserve during exercise that is associated with high filling pressures and inadequate CO responses. These findings highlight the importance of biventricular dysfunction in HFpEF and suggest that novel therapies targeting myocardial reserve in both the left and right heart may be effective to improve clinical status.
Source: European Heart Journal - Category: Cardiology Authors: Tags: Heart failure/cardiomyopathy Source Type: research