Hydronephrosis in the Wnt5a-ablated kidney is caused by an abnormal ureter-bladder connection.

This study shows that Wnt5a is not required for development of the renal medulla and that loss of the renal medullary region in the Wnt5a-deleted kidney is caused by an abnormal ureter-bladder connection. PMID: 27923152 [PubMed - as supplied by publisher]

https://www.ncbi.nlm.nih.gov/pubmed/27923152?dopt=Abstract

Source: Differentiation - December 2, 2016 Category: Research Authors: Yun K, Perantoni AO Tags: Differentiation Source Type: research