Question 11: How should Allergic Bronchopulmonary Aspergillosis [ABPA] be managed in Cystic Fibrosis?

Aspergillus fumigatus is a ubiquitous, filamentous and spore-bearing fungus which usually grows at 37 degrees Celsius. It can be an opportunistic pathogen and can induce an inflammatory response in the airways through the production of various toxic and allergenic exoproducts. As a consequence, the clinical presentation may take a number of forms: Allergic bronchopulmonary aspergillosis (ABPA), aspergillus bronchitis, invasive pulmonary aspergillosis and an aspergilloma. ABPA occurs almost exclusively in asthma or cystic fibrosis (CF) patients [1].
Source: Paediatric Respiratory Reviews - Category: Respiratory Medicine Authors: Tags: Cystic Fibrosis: Frequently Asked Questions Source Type: research