Research and Reviews in the Fastlane 163

This study found an OR of 1.16 (0.92-1.46) for mortality in the group that received antibiotics > 3 hours after triage. No one is arguing to withhold antibiotics from septic patients. Rather, we should avoid giving everyone antibiotics simply to meet a quality measure that isn’t based on data. Recommended by Anand Swaminathan Emergency Medicine Ferguson I et al. Propofol or Ketofol for Procedural Sedation and Analgesia in Emergency Medicine-The POKER Study: A Randomized Double-Blind Clinical Trial. Annals of emergency medicine. 68(5):574-582.e1. 2016. PMID: 27460905 We now have another study, this time a multicenter RTC, comparing propofol to 1:1 ketofol for ED procedural sedation. Similar to smaller previous studies, no difference was found in the primary outcome of adverse respiratory events requiring intervention. Authors did report an increased incidence of hypotension in the propofol group, however this did not appear to be clinically significant. Although ketofol yet again failed to emerge as superior to propofol alone, some interesting trends in secondary outcomes, including sedation and pain scores, as well as recovery time, warrant further study. Recommended by Meghan Spyres Pediatrics Kaufman J et al. Quick-Wee: a novel non-invasive urine collection method. Emergency medicine journal : EMJ. 2016. PMID: 27565196 I have been christened by all my children while changing diapers and have determined (via rigorous scientific methods) the probability o...
Source: Life in the Fast Lane - Category: Emergency Medicine Authors: Tags: Education Emergency Medicine Pediatrics R&R in the FASTLANE Resuscitation EBM literature recommendations research and reviews Source Type: blogs