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Woman becomes mother to own GRANDCHILD by having surrogate baby for daughter

Jessica Bradford, from Gwent, Wales, was left infertile from chemotherapy and had her eggs frozen three years ago. In May, one of her embryos was inserted into Julie's womb.
Source: the Mail online | Health - Category: Consumer Health News Source Type: news

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Authors: Fung C, Dinh P, Ardeshir-Rouhani-Fard S, Schaffer K, Fossa SD, Travis LB Abstract Testicular cancer has become the paradigm of adult-onset cancer survivorship, due to the young age at diagnosis and 10-year relative survival of 95%. This clinical review presents the current status of various treatment-related complications experienced by long-term testicular cancer survivors (TCS) free of disease for 5 or more years after primary treatment. Cardiovascular disease and second malignant neoplasms represent the most common potentially life-threatening late effects. Other long-term adverse outcomes include neuro...
Source: Advances in Urology - Category: Urology & Nephrology Tags: Adv Urol Source Type: research
Researchers have described the mechanism that explains infertility in women who undergo chemotherapy, a study inNature Structural& Molecular Biology suggests.Science Daily
Source: Society for Endocrinology - Category: Endocrinology Source Type: news
(Goethe University Frankfurt) One of the most significant impairments of the quality of life after a chemotherapy is infertility. Researchers of the Goethe University and the University Tor Vergata in Rome have now identified the mechanism of chemotherapy-induced infertility in females.
Source: EurekAlert! - Social and Behavioral Science - Category: International Medicine & Public Health Source Type: news
Abstract Purpose To provide current recommendations about fertility preservation for adults and children with cancer. Methods A systematic review of the literature published from January 2013 to March 2017 was completed using PubMed and the Cochrane Library. An Update Panel reviewed the identified publications. Results There were 61 publications identified and reviewed. None of these publications prompted a significant change in the 2013 recommendations. Recommendations Health care providers should initiate the discussion on the possibility of infertility with patients with cancer treated during their reproductive...
Source: Clinical Breast Cancer - Category: Cancer & Oncology Authors: Tags: J Clin Oncol Source Type: research
Abstract The obligate intracellular bacterium Chlamydia is a widespread human pathogen that causes serious problems including (but not limited to) infertility and blindness. Our search for novel antichlamydial metabolites from marine-derived microorganisms led to isolation of pyocyanin, a small compound from Pseudomonas aeruginosa Pyocyanin is an effective antichlamydial for all three Chlamydia spp. tested. It has an IC50 of 0.019 ∼ 0.028 μM, which is comparable to the IC50 of tetracycline. At concentrations as low as 0.0039 μM, pyocyanin disables infectivity of the chlamydial elementary body (EB). At 0....
Source: Antimicrobial Agents and Chemotherapy - Category: Microbiology Authors: Tags: Antimicrob Agents Chemother Source Type: research
This study utilizes a unique population database to compare the incidence of several diseases in children (F1 generation) of men exposed to chemotherapy (F0 generation) relative to an unexposed control.
Source: The Journal of Urology - Category: Urology & Nephrology Authors: Tags: Infertility: Epidemiology & Evaluation II Source Type: research
Testis cancer presents a unique problem in male fertility preservation. As many as 50-70% of patients diagnosed with testis cancer are subfertile at the time of diagnosis and up to 15% are azoospermic. Many patients will also require adjuvant radiotherapy or chemotherapy further complicating future fertility potential. In this video, we aim to provide a step-by-step guide to the performance of microsurgical onco-testicular sperm extraction (onco-TESE) in the setting of radical orchiectomy for testis cancer in an azoospermic patient.
Source: The Journal of Urology - Category: Urology & Nephrology Authors: Tags: ED, Infertility & Male Incontinence Source Type: research
Due to recent advances in medical technologies, cancer has become more curable and chronic, and post-treatment quality of life, including male fertility, has become an important issue. Semen cryopreservation is generally recommended for patients who will receive cancer chemotherapy. We have retrospectively reviewed the usage rate of cryopreserved semen samples for cancer patients in our institution.
Source: The Journal of Urology - Category: Urology & Nephrology Authors: Tags: Infertility: Therapy II Source Type: research
Many treatments in pediatrics beyond chemotherapy and radiotherapy delivered to oncology patients affect future fertility. Steroids, psychiatric medications, antiepileptic drugs, thyroid medications, novel biologic agents, and illicit drugs can affect fertility in the short- and long-term. In addition, many drugs used in oncology, such as cyclophosphamide, are deployed now in other subspecialties. Some disorders also have intrinsic risks of infertility.
Source: The Journal of Pediatrics - Category: Pediatrics Authors: Tags: The Editors' Perspectives Source Type: research
This study aims to evaluate whether cancer treatments differ in infertile men compared to men who have undergone vasectomy and age‐matched controls. We analyzed subjects from the Truven Health MarketScan Claims database from 2001 to 2009. Infertile men were identified through diagnosis and treatment codes. Comparison groups included vasectomized men and an age‐matched cohort who were not infertile and had not undergone vasectomy. We considered cancer types previously associated with infertility that were diagnosed after the diagnosis of infertility. The treatment regimens were determined based on the presence of claims...
Source: Andrology - Category: Urology & Nephrology Authors: Tags: Original Article Source Type: research
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