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Data points to no age-related cutoff for mammogram screenings | RSNA 2016 Roundup

There is no clear cut-off age to stop breast cancer screening, according to new data from the largest-ever study on mammogram screening outcomes. Data from the study was presented this week at the Radiological Society of North America’s annual meeting. Age-based cutoffs for screenings have been a source of controversy for many years in the healthcare field. Results from the massive study, however, support guidelines that support making breast cancer screening decisions based on individual patients and health status over a specific age, according to study researchers. Data in the study came from over 5.6 million mammogram screenings performed over 7 years between January 2008 and December 2014 and across 150 facilities in 31 U.S. states. Patient demographic data, mammography and biopsy results were considered in the analysis, with over 2.5 million women over 40 in the study. A total of 4 standard performance metrics were used to evaluate the data at each age group, including cancer detection rate, recall rate, positive predictive value for biopsies and biopsies performed. The mean rate of cancer detection was clocked at 3.74 per 1,000 patients, with a recall rate of 10%, positive predictive value of recommended biopsies at 20% and for biopsies performed at 29%. In considering age between 40 and 80 years, metrics showed a gradualte upward trend in terms of cancer detection rate and biopsy prediction rate, but a downward trend in recall rate. “All prior randomized, c...
Source: Mass Device - Category: Medical Equipment Authors: Tags: Imaging Oncology Radiological Society of North America Source Type: news

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ConclusionBreast cancer subtypes are associated with different time and pattern of recurrence and it should be considered during treatment decision.
Source: Journal of Cancer Research and Clinical Oncology - Category: Cancer & Oncology Source Type: research
Google (NSDQ:GOOG) this week presented initial data from a prototype augmented reality microscope platform it’s developing for advanced cancer detection, according to a research blog post from the tech giant. The platform consists of a modified light microscope for real-time image analysis and presents analysis from a machine-learning algorithm directly into the users field of view, Google said. Google said the platform could be retrofitted into existing light microscopes generally used in hospitals and clinics using low-cost, readily-available components without the need for digital versions of the scopes. The ...
Source: Mass Device - Category: Medical Devices Authors: Tags: Imaging Research & Development google Source Type: news
(UNC Lineberger Comprehensive Cancer Center) In a preliminary study presented at the American Association for Cancer Research Annual Meeting 2018 in Chicago, researchers from the UNC Lineberger Comprehensive Cancer Center revealed findings for what kind of immune response the body is staging against triple negative breast cancer that has spread to the brain. They hope they can use these findings to improve patient responses to drugs that work by unleashing the immune system against cancer.
Source: EurekAlert! - Medicine and Health - Category: International Medicine & Public Health Source Type: news
A woman's body fat index measured by ultrasound appears to be a better gauge...Read more on AuntMinnie.comRelated Reading: DTI-MRI links maternal obesity to newborn brain growth Study: Do fetal anatomy US scans earlier in obese women Obese patients require special attention during rad therapy Obese women less likely to complete mammograms Obese women less likely to survive breast cancer, even after treatment
Source: AuntMinnie.com Headlines - Category: Radiology Source Type: news
Brain metastases (BM) are the most common intracranial neoplastic disease in adults, with an incidence of 9-17% among all brain tumors (Nayak et al., 2012). They are usually caused by lung cancer (either non-small cell (NSCLC) and small cell (SCLC) histologies), breast cancer, melanoma and renal cell carcinoma, with a raising incidence related to the improvements in diagnostic and treatment approaches (Berghoff et al., 2014). However, prognosis remains poor, with a median overall survival (OS) ranging from 3 to 27 months (Brastianos et al., 2013), rendering BM still an unmet medical need.
Source: Critical Reviews in Oncology Hematology - Category: Cancer & Oncology Authors: Source Type: research
“Live life to the fullest.” “Celebrate life.” “Carpe diem.” I’ve heard them all. But what if I don’t feel like it? What if I’m having a lousy brain day, restricted to a darkened room with a blinding headache, and seizing the day is not an option? I have clusters of malformed blood vessels called cavernous angiomas in my brain. Two of them bled, turning my life upside down with seizures and other symptoms. A few months later, I underwent resection surgeries to prevent future bleeds. The surgeries wreaked additional havoc — headaches, seizures, fatigue, short attent...
Source: World of Psychology - Category: Psychiatry & Psychology Authors: Tags: Brain Blogger Health-related Personal Publishers carpe diem celebrate life Fear Personality Seize the Day Source Type: blogs
This report is the first to suggest potential approaches to BM treatment using this scheme and describes the effects of an apatinib-containing regimen on BMs.
Source: Medicine - Category: Internal Medicine Tags: Research Article: Clinical Case Report Source Type: research
Authors: Masood A, Masood K, Hussain M, Ali W, Riaz M, Alauddin Z, Ahmad M, Masood M, Shahid A Abstract This research was conducted to generate trends and patterns of most common male and female cancers from 1984-2014 for the city population of Lahore Pakistan. Cancer incidence data gathered for different organs were processed through cleaning, integration, transformation, reduction and mining for ultimate representation. Risk of cancer appeared to be continuously increasing among both males and females. Overall, lymphomas and breast cancer are the most common neoplasm in males and females, respectively, in Lahore ...
Source: Asian Pacific Journal of Cancer Prevention - Category: Cancer & Oncology Tags: Asian Pac J Cancer Prev Source Type: research
Condition:   Breast Cancer Interventions:   Drug: Atezolizumab;   Procedure: Stereotactic radiosurgery (SRS) Sponsors:   Dana-Farber Cancer Institute;   Genentech, Inc. Not yet recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
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