Outcome of pregnancy and neonatal complications with anti-tumor necrosis factor- α use in females with immune mediated diseases; a systematic review and meta-analysis.

CONCLUSIONS: Female patients with immune mediated diseases treated with anti-TNF-α agents were at significantly increased risks of preterm birth, spontaneous abortion and low birth weight compared to the general population, but had comparable outcomes with non-users. These results provide useful information for female patients in their reproductive age and raise awareness of the conditions that they are facing among clinicians managing their care. PMID: 27913060 [PubMed - as supplied by publisher]

https://www.ncbi.nlm.nih.gov/pubmed/27913060?dopt=Abstract

Source: Journal of Autoimmunity - November 28, 2016 Category: Allergy & Immunology Authors: Komaki F, Komaki Y, Micic D, Ido A, Sakuraba A Tags: J Autoimmun Source Type: research