Epidemiologic and therapeutic aspects of refractory coeliac disease - a systematic review.

CONCLUSION: RCD is a very rare disease. The current evidence for RCDI treatment includes prednisolone in combination with the immunosuppressants azathioprine, mesalamine or tioguanine. The current evidence for RCDII treatment documents use of the antimetabolite cladribine, and if there is no effect, autologous haematopoetic stem cell transplantation may be attempted. In the future, there is a need for more effective treatments which will also prevent further progression to enteropathy-associated T-cell lymphoma. PMID: 27910801 [PubMed - in process]
Source: Danish Medical Journal - Category: Journals (General) Tags: Dan Med J Source Type: research