Production of TNF-alpha ex vivo is predictive of an immune response to flu vaccination in a frail elderly population.

CONCLUSION: Production of TNFα appears to be primordial for an efficient vaccine response, and may provide a predictive marker for the humoral response to vaccination. It may also provide the basis for evaluating agents designed to rescue TNFα-producing cells. This study emphasises a need to rescue TNF-producing cell function. PMID: 27910810 [PubMed - in process]
Source: European Cytokine Network - Category: Molecular Biology Tags: Eur Cytokine Netw Source Type: research