Hyperlipidemia-Mediated Increased advanced lipoxidation end products Formation, an Important Factor Associated with Decreased Erythrocyte glucose-6-phosphate dehydrogenase Activity in Mild Nonproliferative Diabetic Retinopathy

Conclusions Hyperlipidemia is an important factor that is associated with increased ALEs formation in persons with MNPDR. Increased ALEs generation was associated with decreased G6PD activity and low NADPH levels in cases of MNPDR, suggesting their detrimental role in the occurrence of early NPDR.
Source: Canadian Journal of Diabetes - Category: Endocrinology Source Type: research