MEK and TAK1 Regulate Apoptosis in Colon Cancer Cells with KRAS-Dependent Activation of Proinflammatory Signaling

This study describes a potential therapeutic strategy for a subset of colon cancers that are dependent on oncogenic KRAS signaling pathways, which are currently difficult to block with selective agents. Mol Cancer Res; 14(12); 1204–16. ©2016 AACR.

Source: Molecular Cancer Research - November 30, 2016 Category: Cancer & Oncology Authors: McNew, K. L., Whipple, W. J., Mehta, A. K., Grant, T. J., Ray, L., Kenny, C., Singh, A. Tags: Cell Death and Survival Source Type: research