Functional Gonadotroph Adenomas: Case Series and Report of Literature

CONCLUSION: An FGA can pose both a diagnostic and a therapeutic challenge. The tumor is often diagnosed as a nonfunctioning macroadenoma after presenting with nonspecific symptoms and is the cause of significant morbidity. An FGA should be considered in the differential diagnosis of patients harboring pituitary adenomas with reproductive dysfunction. Transsphenoidal resection is the initial treatment of choice and can reduce endocrine dysfunction, resolve headaches, improve visual impairment, and provide tissue for detailed analysis. ABBREVIATIONS: FGA, functional gonadotroph adenoma FSH, follicle-stimulating hormone LH, luteinizing hormone TSH, thyroid-stimulating hormone
Source: Neurosurgery - Category: Neurosurgery Tags: Research-Human-Clinical Studies Source Type: research