Diffusion Tensor Imaging: A Possible Biomarker in Severe Traumatic Brain Injury and Aneurysmal Subarachnoid Hemorrhage?
CONCLUSION: DTI parameters, assessed at approximately day 12 after injury, correlated with mortality at 6 months in patients with severe TBI or aSAH. Similar patterns were found for both TBI and aSAH patients. This supports a potential role of DTI as early endpoint for clinical studies and a predictor of late mortality.
ABBREVIATIONS: aSAH, aneurysmal subarachnoid hemorrhage
DTI, diffusion tensor imaging
FA, fractional anisotropy
GOSE, Glasgow Outcome Scale Extended
TBI, traumatic brain injury
TE, echo time
TR, repetition time
Source: Neurosurgery - Category: Neurosurgery Tags: Research-Human-Clinical Studies Source Type: research