RKIP and TBK1 form a positive feedback loop to promote type I interferon production in innate immunity

This study reveals a previously unrecognized positive feedback loop between RKIP and TBK1 that is essential for type I interferon production in anti-viral innate immunity.

Source: EMBO Journal - November 30, 2016 Category: Molecular Biology Authors: Gu, M., Liu, Z., Lai, R., Liu, S., Lin, W., Ouyang, C., Ye, S., Huang, H., Wang, X. Tags: Immunology Articles Source Type: research