Identifying Chemical Groups for Biomonitoring

Conclusion We construct broad functional and structural chemical groups to proactively and efficiently capture chemicals of potential concern for inclusion in Biomonitoring California. These groups encompass chemicals already in high use, as well as related chemicals that may later emerge as exposure and health concerns. Listing of broad groups allows us to keep up with market shifts and respond to other new information in choosing chemicals to measure. The chemical selection strategy described in this paper can be applied in other monitoring, testing, and assessment programs to support early action on emerging chemicals. Ultimately, taking a more comprehensive approach to identifying chemicals with potential exposure and toxicity concerns will improve the protection of public health and the environment. References Attene-Ramos MS, Miller N, Huang R, Michael S, Itkin M, Kavlock RJ, et al. 2013. The Tox21 robotic platform for the assessment of environmental chemicals—from vision to reality. Drug Discov Today 18(15–16):716–723. Ballesteros-Gómez A, Brandsma SH, de Boer J, Leonards PE. 2014a. Analysis of two alternative organophosphorus flame retardants in electronic and plastic consumer products: resorcinol bis-(diphenylphosphate) (RBDPP) and bisphenol A bis (diphenylphosphate) (BPA-BDPP). Chemosphere 116:10–14, doi: 10.1016/j.chemosphere.2013.12.099. Ballesteros-Gómez A, de Boer J, Leonards P. 2014b. A novel brominated triazine-based flame retardant (TTBP-TAZ) in pl...
Source: EHP Research - Category: Environmental Health Authors: Tags: Perspectives Brief Communications December 2016 Source Type: research