Clinical Complete Response from Chemotherapy in an Elderly Patient with Metastatic Gastric Cancer: A Case Report.

Clinical Complete Response from Chemotherapy in an Elderly Patient with Metastatic Gastric Cancer: A Case Report.
J Nippon Med Sch. 2016;83(5):199-202
Authors: Kawagoe T, Maruki Y, Nagoya H, Kosugi Y, Akimoto T, Yamawaki H, Kodaka Y, Shimpuku M, Ueki N, Futagami S, Miyake K, Iwakiri K
Abstract
An 81-year-old man was admitted with upper abdominal pain and weight loss. Esophagogastroduodenoscopy revealed a large tumor located from the gastric angle to the body. Histological analysis of a biopsy revealed a moderately differentiated adenocarcinoma. Computed tomography revealed metastases in the liver and lung and the patient was subsequently diagnosed with metastatic advanced gastric cancer. He was treated with chemotherapy using S-1 (80 mg/m(2)) and cisplatin (CDDP) (60 mg/m(2)). Twenty-two months after chemotherapy, the gastric tumor, and the nodules in the liver and lung, had disappeared. We subsequently diagnosed a clinical complete response. The patient was treated with further S-1 monotherapy for 7 months after complete response assessment. He has lived for more than 7 years since the initial diagnosis without recurrence. Chemotherapy using S-1 and CDDP may be a potent strategy for improving survival in elderly patients with advanced gastric cancer.
PMID: 27890894 [PubMed - in process]

Source: Journal of Nippon Medical School - November 30, 2016 Category: Universities & Medical Training Authors: Kawagoe T, Maruki Y, Nagoya H, Kosugi Y, Akimoto T, Yamawaki H, Kodaka Y, Shimpuku M, Ueki N, Futagami S, Miyake K, Iwakiri K Tags: J Nippon Med Sch Source Type: research