Internal and external generalizability of temporal dose-response relationships for xerostomia following IMRT for head and neck cancer.
CONCLUSIONS: Increased Dmeancontra and Dmeanipsi explain short-term xerostomia following IMRT. Our results also suggest decreasing Dmeancontra to below 20Gy, while keeping Dmeanipsi to around 25Gy. Long-term xerostomia was less frequent, and no dose-response relationship was established for this follow-up time.
PMID: 27890427 [PubMed - as supplied by publisher]
Source: Radiotherapy and Oncology : journal of the European Society for Therapeutic Radiology and Oncology - Category: Radiology Authors: Thor M, Owosho AA, Clark HD, Oh JH, Riaz N, Hovan A, Tsai J, Thomas SD, Yom SH, Wu JS, Huryn JM, Moiseenko V, Lee NY, Estilo CL, Deasy JO Tags: Radiother Oncol Source Type: research
More News: Cancer | Cancer & Oncology | Head and Neck Cancer | Intensity-Modulated Radiation Therapy | Radiology | Study | Xerostomia