[Vitamin D metabolism and signaling in human hepatocellular carcinoma and surrounding non-tumorous liver].

CONCLUSIONS: The presence of CYP24A1 mRNA and the reduced expression of VDR and CYP27B1 mRNA in human hepatocellular carcinoma samples indicate decreased bioavailability of 1,25-Dihydroxy vitamin D3, providing an escape mechanism from the anti-tumor effect. Orv. Hetil., 2016, 157(48), 1910-1918.
PMID: 27889974 [PubMed - in process]

Source: Orvosi Hetilap - October 31, 2016 Category: Journals (General) Authors: Horváth E, Balla B, Kósa J, Lakatos PA, Lazáry Á, Németh D, Jozilan H, Somorácz Á, Korompay A, Gyöngyösi B, Borka K, Kiss A, Kupcsulik P, Schaff Z, Szalay F Tags: Orv Hetil Source Type: research