A β Amyloid Pathology Affects the Hearts of Patients With Alzheimer’s Disease Mind the Heart

ConclusionsHere, the authors provide the first report of the presence of compromised myocardial function and intramyocardial deposits of A β in AD patients. The findings depict a novel biological framework in which AD may be viewed either as a systemic disease or as a metastatic disorder leading to heart, and possibly multiorgan failure. AD and HF are both debilitating and life-threatening conditions, affecting enormous patient pop ulations. Our findings underline a previously dismissed problem of a magnitude that will require new diagnostic approaches and treatments for brain and heart disease, and their combination.
Source: Journal of the American College of Cardiology - Category: Cardiology Source Type: research