Distinct in vitro Complement Activation by Various Intravenous Iron Preparations.

CONCLUSION: This study provides evidence that iron dextran and ferric carboxymaltose have complement-activating capacities in-vitro, and hypersensitivity reactions to these drugs could be CARPA-mediated.
PMID: 27889746 [PubMed - as supplied by publisher]

Source: American Journal of Nephrology - November 25, 2016 Category: Urology & Nephrology Authors: Hempel JC, Poppelaars F, Gaya da Costa M, Franssen CF, de Vlaam TP, Daha MR, Berger SP, Seelen MA, Gaillard CA Tags: Am J Nephrol Source Type: research