Left ventricular end-diastolic volume as an early indicator of Trastuzumab-related cardiotoxicity in patients with HER2 positive breast cancer: results from a single-center retrospective study.

CONCLUSIONS: Prevalence of Trastuzumab-related cardiotoxicity in patients with HER2-positive early breast cancer is relatively frequent, although asymptomatic in most cases. Baseline EDV resulted as independent predictor of cardiotoxicity suggesting that EDV may be more reliable than LVEF to identify patients at higher risk of developing cardiac damage. PMID: 27886160 [PubMed - as supplied by publisher]
Source: Minerva Cardioangiologica - Category: Cardiology Tags: Minerva Cardioangiol Source Type: research