Sublingual immunotherapy for mite allergic rhinitis.

SUBLINGUAL IMMUNOTHERAPY FOR MITE ALLERGIC RHINITIS. Arerugi. 2016;65(9):1187-1191 Authors: Okamoto Y PMID: 27885202 [PubMed - in process]
Source: Allergology International - Category: Allergy & Immunology Tags: Arerugi Source Type: research

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This article will review different methods of skin testing available for allergic rhinitis, emphasizing controversies and challenges associated with these techniques.Recent FindingsThe utility of quantitative skin testing has been debated in current literature, as has the accuracy of skin versus in vitro testing. Single- and pauci-allergen immunotherapy (AIT) have also shown good outcomes, thus questioning the use of large testing panels. Recent studies further support the use of standardized and recombinant antigens.SummarySkin testing remains a safe and dependable tool in the diagnosis and management of allergic rhinitis...
Source: Current Otorhinolaryngology Reports - Category: ENT & OMF Source Type: research
Subcutaneous immunotherapy is the only treatment that improves the natural progression of allergic rhinitis and maintains long-term outcomes after discontinuation of the drug. Metabolomics is increasingly applied in the study of allergic diseases, including allergic rhinitis. However, little is known about the discovery of metabolites that can evaluate clinical efficacy and possible mechanisms of Artemisia sieversiana pollen subcutaneous immunotherapy. Thirty-three patients with Artemisia sieversiana pollen allergic rhinitis significantly improved after 1-year subcutaneous immunotherapy treatment, while ten patients were i...
Source: Frontiers in Pharmacology - Category: Drugs & Pharmacology Source Type: research
ConclusionAlthough a larger number of patients for a longer follow ‐up period are needed to precisely assess the treatment efficacy, AIT using cat and/or dog dander may be an effective treatment option for AD patients, especially for severe AD patients with other respiratory allergic comorbidities who cannot completely avoid the exposure to animal dander.
Source: Immunity, Inflammation and Disease - Category: Allergy & Immunology Authors: Tags: ORIGINAL RESEARCH Source Type: research
Authors: Devillier P, Demoly P, Molimard M Abstract Introduction: Randomized controlled trials (RCTs) show that allergen immunotherapy (AIT) has proven long-term efficacy in patients with allergic rhinitis (AR). However, RCTs have limited generalizability and there is growing recognition that real-world evidence (RWE) is necessary to provide complementary data to those of RCTs, and corroborate their findings. Until recently, data from the real-world setting investigating the benefits of AIT for the treatment of patients with grass and birch pollen-associated AR were sparse, but new retrospective claims database stu...
Source: Expert Review of Respiratory Medicine - Category: Respiratory Medicine Tags: Expert Rev Respir Med Source Type: research
This study aims to assess the clinical relevance of serum inhibitory activity for I...
Source: Allergy, Asthma and Clinical Immunology - Category: Allergy & Immunology Authors: Tags: Research Source Type: research
Purpose of review In allergy, personalized medicine passes through the assessment of molecular allergens sensitization profiles. Such technique may help to better diagnose and treat patients suffering from allergic respiratory diseases. Recent findings Different laboratory tests are available today to assess sensitization to molecular allergens, from singleplex assays, to unspecific, screening multiplex assays, mainly performed through microarrays or macroarrays. It is important to collect both results from specific IgE toward allergen extracts and toward molecular allergens, to collect the most complete information o...
Source: Current Opinion in Allergy and Clinical Immunology - Category: Allergy & Immunology Tags: PEDIATRIC ASTHMA AND DEVELOPMENT OF ATOPY: Edited by Andy Liu and Pasquale Comberiati Source Type: research
The objectives were to examine physician and patient perceptions of seasonal allergy symptoms ...
Source: Allergy, Asthma and Clinical Immunology - Category: Allergy & Immunology Authors: Tags: Research Source Type: research
AbstractPurpose of ReviewPrecision medicine (PM) represents a new paradigm in disease diagnosis, prevention, and treatment. The PM approach focuses on the characterization of different phenotypes and pathogenic pathways in order to allow the selection of specific biomarkers that will be useful in disease management. Rhinitis is a highly prevalent and heterogeneous disease, both in terms of underlying endotypes and clinical presentations. Therefore, to apply the PM principles to the various rhinitis subtypes rise as a meaningful strategy to improve evaluation and treatment.Recent FindingsThe technology of recombinant allerg...
Source: Current Treatment Options in Allergy - Category: Allergy & Immunology Source Type: research
Publication date: February 2020Source: The Journal of Allergy and Clinical Immunology: In Practice, Volume 8, Issue 2Author(s): Nicole Akar-Ghibril, Thomas Casale, Adnan Custovic, Wanda PhipatanakulAllergic asthma is defined as asthma associated with sensitization to aeroallergens, which leads to asthma symptoms and airway inflammation. Allergic asthma is the most common asthma phenotype. The onset of allergic asthma is most often in childhood and is usually accompanied by other comorbidities including atopic dermatitis and allergic rhinitis. It is often persistent although there is a wide variation in disease severity. It...
Source: The Journal of Allergy and Clinical Immunology: In Practice - Category: Allergy & Immunology Source Type: research
Temperate grass (e.g. ryegrass) pollen is a major driver of seasonal allergic rhinitis (SAR) and asthma risks, including thunderstorm asthma. Patients in this high-risk population are frequently poly-sensitized to subtropical grass pollens. Whether this affects their response to temperate grass pollen allergen immunotherapy (AIT) is unknown. We determined the impact of sensitization to subtropical grass pollen upon effectiveness of 5-grass pollen SLIT tablets in SAR.
Source: Journal of Allergy and Clinical Immunology - Category: Allergy & Immunology Authors: Source Type: research
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