Pathogenetic implications of the age at time of diagnosis and skin location for acrodermatitis chronica atrophicans

Conclusions ACA is more likely to be diagnosed in older individuals than any other manifestation of Lyme borreliosis. ACA is more likely than EM to be localized anatomically to the extremities. Available data favor the hypothesis that ACA occurs most often on the extremities of older individuals because of predisposing age-related anatomic or physiologic changes, but more data are needed to define the latency period and other aspects of the pathogenesis of this skin condition.
Source: Ticks and Tick borne Diseases - Category: Zoology Source Type: research