Just a small cut in saturated fats 'reduces heart disease risk'

Conclusion This study shows an association between increased intake of individual saturated fats and increased risk of coronary heart disease. It also shows a link between the replacement of these fatty acids with other types of fat, plant protein, or wholegrain carbohydrates and a reduction in coronary heart disease risk. The strengths of this study are the large sample size and long follow-up period that looked at repeated measures such as diet, lifestyle and health outcomes. It also provides clear support for dietary guidelines that recommend replacing dietary energy from saturated fats with polyunsaturated fats as well as wholegrain carbohydrates and plant source proteins. However, there are a number of limitations to the study: Although the study adjusted for confounding variables, there may be other factors that were not accounted for. For example, stress and life events might be contributors to coronary heart disease, but were not measured. The analysis was based on self-reported dietary intake and therefore may be subject to recall bias. The study populations were comprised of health professionals who might have very similar lifestyles to one another; therefore the results may not be representative of other populations. Finally, most people did not just eat only one type of saturated fat, so it is hard to disentangle which have more association with coronary heart disease. Also, the study did not consider other types of fatty acids, such as those found in da...
Source: NHS News Feed - Category: Consumer Health News Tags: Heart/lungs Food/diet Source Type: news

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ConclusionThere is a paucity of treatment guidelines for acute lung injury secondary to marijuana inhalation. We advocate early use of short-term steroids and also more awareness on quitting marijuana smoking to prevent life-threatening complications like myocardial infarction, diffuse alveolar hemorrhage and acute respiratory distress syndrome.
Source: Heart and Lung: The Journal of Acute and Critical Care - Category: Respiratory Medicine Source Type: research
ABSTRACT Introduction: Cervicovaginal atrophy is a condition that can affect women after menopause, and cytology is a diagnostic tool useful in such cases. Objective: To evaluate the cytomorphological profile of cervical smears in patients over 60 years old. Methods: Cytopathological examinations of 500 patients over 60 years old were selected consecutively in this cross-sectional, quantitative, retrospective study. Results: Only 114 (22.8%) presented the squamocolumnar junction (SCJ) sampled, and their presence decreased progressively with advancing age (p
Source: Jornal Brasileiro de Patologia e Medicina Laboratorial - Category: Pathology Source Type: research
Conclusion: There is no association between the allele frequencies, genotype, inheritance models and haplotypes of the rs4711998 A>G, rs8193036 C>T and rs2275913 A>G polymorphisms of the IL17A gene and PE.RESUMEN Introducci ón: La preeclampsia (PE) se define como hipertensión arterial asociada a proteinuria después de la semana 20 de gestación en mujeres anteriormente normotensas. La interleucina 17ª (IL17A) es un inductor potente de inflamación tisular y polimorfismos del gen IL17A pueden modular la expresión g énica y afectar las funciones de las célul...
Source: Jornal Brasileiro de Patologia e Medicina Laboratorial - Category: Pathology Source Type: research
Conclusion: We found a high rate of hyperuricemia in children with DS that equally affects both genders, except in the age range of 13-15 years, in which it was more common among females.RESUMEN Introducci ón: Pacientes con síndrome de Down (SD) perecen tener mayor grado de hiperuricemia, aunque hay pocos estudios que traten esa cuestión. Niveles elevados de ácido úrico (AU) son un factor de riesgo independiente para enfermedad cardiovascular aterosclerótica. Objetivo: Estudiar la prevalencia d e hiperuricemia en niños y adolescentes con SD y su distribución de acuerd...
Source: Jornal Brasileiro de Patologia e Medicina Laboratorial - Category: Pathology Source Type: research
Publication date: Available online 25 April 2019Source: Journal of Minimally Invasive GynecologyAuthor(s): Omur Taskin, Kiran Rikhraj, Justin Tan, Tara Sedlak, Timothy C. Rowe, Mohamed A. BedaiwyAbstractEndometriosis and atherosclerotic cardiovascular disease (ASCVD) are both essentially diseases of inflammation. It is well established that inflammation is the leading mechanism in the initiation and maintenance of vascular injury and in the development and progression of atherosclerosis. Thus, if women with endometriosis do indeed have increased general inflammation, they are at increased risk of developing microvascular d...
Source: Journal of Minimally Invasive Gynecology - Category: OBGYN Source Type: research
Conclusion: Patients with prior stroke may be the preferred group for LAAC regardless of the presence or absence of contraindications for anticoagulant therapy.
Source: Cerebrovascular Diseases - Category: Neurology Source Type: research
In this study, we examined the benefits of early-onset, lifelong AET on predictors of health, inflammation, and cancer incidence in a naturally aging mouse model. Lifelong, voluntary wheel-running (O-AET; 26-month-old) prevented age-related declines in aerobic fitness and motor coordination vs. age-matched, sedentary controls (O-SED). AET also provided partial protection against sarcopenia, dynapenia, testicular atrophy, and overall organ pathology, hence augmenting the 'physiologic reserve' of lifelong runners. Systemic inflammation, as evidenced by a chronic elevation in 17 of 18 pro- and anti-inflammatory cytokin...
Source: Fight Aging! - Category: Research Authors: Tags: Newsletters Source Type: blogs
Conclusion: In post-menopausal women, lower HRV was associated with a modestly higher, but statistically significant, risk for incident cardiovascular events, including fatal and non-fatal myocardial infarction. Factors associated with lower HRV and cardiac autonomic impairment may be candidates for reducing CHD risk, such as better glycemic control and improved physical activity.
Source: Circulation: Cardiovascular Quality and Outcomes - Category: Cardiology Authors: Tags: Session Title: Predicting the Future Source Type: research
Conclusion This large pooled cohort study seems to demonstrate an association between a healthy plant-based diet and reduced risk of coronary heart disease, and an increased risk of heart disease with an unhealthy plant-based diet. This adds to the evidence base supporting the possible benefits of healthy plant-based diets in protecting against certain illnesses. However there are some limitations to the research: The cohort included only health professionals from the US so might not be representative of wider populations in the UK or elsewhere. The study can't provide information on the benefits or otherwise of this d...
Source: NHS News Feed - Category: Consumer Health News Tags: Food/diet Source Type: news
Conclusion This study has found that while overall gluten consumption in people without coeliac disease may not be related to heart disease risk, avoiding whole grains (wheat, barley and rye) in order to avoid gluten may be associated with increased heart disease risk. This study has several strengths, including its large size, the fact that data was collected prospectively and diet assessed at several time-points, the long period of follow up, and that it took into account a wide range of potential confounders. As with all studies of this type, it is possible that other factors may affect the results. However, the researc...
Source: NHS News Feed - Category: Consumer Health News Tags: Food/diet Heart/lungs Source Type: news
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