Performance of native and contrast-enhanced T1 mapping to detect myocardial damage in patients with suspected myocarditis: a head-to-head comparison of different cardiovascular magnetic resonance techniques

AbstractMyocardial T1 mapping is a novel technique that has proven to be superior to standard imaging for differentiation between healthy individuals in acute myocarditis. Aim of this study was comparison of T1 mapping with a clinical biomarker. We retrospectively investigated 171 patients undergoing cardiovascular magnetic resonance (CMR) examination with suspected myocarditis by performing native and contrast enhanced T1-mapping. Additionally, T2w and T1w images and late gadolinium enhancement sequences (LGE) were utilized for myocardial evaluation; Lake Louise Criteria comprise T1w, T2w and LGE imaging in a score. Reference for positive myocarditis diagnosis was a ten-fold increase of troponin level above normal (0.14  ng/ml). Native T1 and extracellular volume (ECV) showed good association with relevant troponin elevations. Area under the curve (AUC) was 81% (p = 0.0001) for native T1 with an optimal threshold of 979 ms and 86% (p 
Source: The International Journal of Cardiovascular Imaging - Category: Radiology Source Type: research

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Conditions:   COVID;   Acute Coronary Syndrome;   Myocardial Infarction;   Myocarditis;   Venous Thromboembolism;   Deep Vein Thrombosis;   Pulmonary Embolism Intervention:   Sponsor:   Centre Hospitalier Universitaire de Nice Recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
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Source: Harvard Health Blog - Category: Consumer Health News Authors: Tags: Health Heart Health Hypertension and Stroke Infectious diseases Source Type: blogs
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Source: Current Awareness Service for Health (CASH) - Category: Consumer Health News Source Type: news
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Source: The Journal of Heart and Lung Transplantation - Category: Transplant Surgery Authors: Tags: (501) Source Type: research
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Source: The Journal of Heart and Lung Transplantation - Category: Transplant Surgery Authors: Tags: (636) Source Type: research
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Source: The Journal of Heart and Lung Transplantation - Category: Transplant Surgery Authors: Tags: (630) Source Type: research
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Source: The Journal of Heart and Lung Transplantation - Category: Transplant Surgery Authors: Tags: (299) Source Type: research
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Source: The Journal of Heart and Lung Transplantation - Category: Transplant Surgery Authors: Tags: (439) Source Type: research
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Source: The Journal of Heart and Lung Transplantation - Category: Transplant Surgery Authors: Tags: (110) Source Type: research
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