Effect of intravenous zoledronic acid infusion on electrocardiographic parameters in patients with osteoporosis

ConclusionsZA infusion did not affect P wave dispersion both at the immediate post-infusion period and 1  month after infusion. QT values were significantly increased early after ZA infusion; however, there were no significant differences in parameters reflecting disparity of ventricular recovery times and transmural dispersion of ventricular repolarization. Based on these observations, it may be sugg ested that ZA infusion did not have any short- or long-term effect on any parameter that might be associated with the tendency for atrial fibrillation or ventricular arrhythmias.
Source: Osteoporosis International - Category: Orthopaedics Source Type: research