Association of ORAI1 Gene Polymorphisms with Chronic Spontaneous Urticaria and the Efficacy of the Nonsedating H1-antihistamine Desloratadine

Human ORAI1 polymorphisms were associated with susceptibility to CSU, and the South Han Chinese CSU who carry rs3741595C allele have reduced responsiveness to nonsedating H1-antihistamines.
Source: Journal of Allergy and Clinical Immunology - Category: Allergy & Immunology Authors: Source Type: research