Hyper-CVAD compared to BFM-like Chemotherapy for the Treatment of Adult Acute Lymphoblastic Leukemia. A Retrospective single center analysis

Several induction regimens have been developed for adult patients with acute lymphoblastic leukemia (ALL). We demonstrate that the hyper-CVAD regimen appears to be feasible for adult patients with ALL in terms of tolerability and efficacy. Addition of TKI for Ph+ cases and rituximab for CD20+ cases were significantly more frequent in the Hyper-CVAD arm and may have affected outcomes favorably. There is still a need for large, prospective, randomized studies in order to establish the best induction regimen for adult ALL patients.
Source: Clinical Lymphoma, Myeloma and Leukemia - Category: Hematology Authors: Tags: Original Study Source Type: research