“Off-Hours” Versus “On-Hours” Presentation in ST-Segment Elevation Myocardial Infarction CHAMPION PHOENIX Findings

Timely percutaneous coronary intervention (PCI) in ST-segment elevation myocardial infarction (STEMI) is a cornerstone of therapy. Several analyses have demonstrated worse outcomes for patients presenting with STEMI during off-hours compared with during the workday(1). The etiology of this difference is likely multifactorial, including changes in staffing, delays in intervention, and higher procedural complications(2). Most available data derive from registries with retrospective collection of clinical characteristics and outcomes, whereas few data are available from randomized, controlled trials (1,3). There continues to be debate regarding whether this effect exists in the contemporary era (1–3). Finally, comprehensive delineation of relevant outcomes, including stent thrombosis, is rarely available from registry data. Such information is crucial to understanding differences in care. We sought to determine whether such differences existed in a large, contemporary, international trial.
Source: Journal of the American College of Cardiology - Category: Cardiology Source Type: research