how hypothyroidism causes carpal tunnel syndrome?

Source: Student Doctor Network - Category: Universities & Medical Training Authors: Source Type: forums

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The objective of this study was to assess the relationship between multiple TF and systemic or musculoskeletal disorders in a sample of young patients.Material and methodA retrospective study was performed of all patients with TF operated in our hospital between 2011 and 2015. Multiple or single TF diagnosis and pathologies such as diabetes mellitus (DM), thyroid dysfunction, carpal tunnel syndrome (CTS), epicondylalgia or DeQuervain's disease were collected. Statistical results included a bivariate analysis and a multiple logistic regression.ResultsTwo hundred and seventy-nine patients with a mean age of 48.45 years ...
Source: Revista Espanola de Cirugia Ortopedica y Traumatologia - Category: Orthopaedics Source Type: research
We report the clinical features of a patient with hereditary ATTR amyloidosis associated with a novel mutation (Y114S, p.Y134S). A 65-year-old Japanese man was admitted to our hospital after a 3-year history of progressive dyspnea on exertion. Five years previously, he presented dysesthesia in both hands caused by carpal tunnel syndrome. A genetic analysis revealed a base pair substitution of adenine to cytosine in the second codon of exon 4, residue 114, in the TTR gene (c.401A>C). The clinical characteristics were progressive cardiomyopathy with a poor vital prognosis, late onset, sporadic case, bilateral carpal tunne...
Source: Internal Medicine - Category: Internal Medicine Tags: Intern Med Source Type: research
ConclusionsThenar atrophy and sensory loss were highly specific in CTS but had limited value in early detection. Due to their low specificity, provocative tests do not appear sufficient enough to establish a definite CTS diagnosis. Only Durkan’s test could possibly be considered initially as it has more balanced values. Diabetes, obesity, rheumatoid arthritis, hypothyroidism and gout significantly increase the risk of CTS.
Source: Journal of Clinical Neuroscience - Category: Neuroscience Source Type: research
ConclusionThis study shows a correlation between sensory and motor axonal loss. A multicenter study is needed to better retain this correlation relationship.
Source: Neurophysiologie Clinique - Category: Neuroscience Source Type: research
This study was conducted to observe the characteristics of the risk factors of carpal tunnel syndrome (CTS) in Chinese population. CTS of 1,512 outpatients aged 41-70 years were without any other diseases which could cause numbness as a case group, and 4,536 non-CTS outpatients as a control group were involved in the study in 2013-2014. Both groups received a questionnaire and the case group received another electrical physiological examination. The results showed the odds ratio (OR) of age is 0.990 (95% CI, 0.984-0.996). The OR of BMI is 1.096 (95% CI, 1.077-1.115). The OR of smoking is 4.862 (95% CI, 3.991-5.925). The OR...
Source: Experimental and Therapeutic Medicine - Category: General Medicine Tags: Exp Ther Med Source Type: research
We report on a 70-year-old right-handed woman who presented with an 11-year history of a gradually progressive motor and cognitive-behavioral syndrome caused by focal cerebral β-amyloid angiopathy manifesting as discrete mass lesions. At age 59, she developed left leg clumsiness and cramping, evolving within a year into leg stiffness. Similar symptoms gradually affected her left arm. At age 65, she noted progressive word-finding difficulties, anxiety, mental rigidity, and compulsive traits. By age 68, she had difficulties with processing speed, planning, and navigation. Her history was notable for mild hypertension, h...
Source: Neurology Clinical Practice - Category: Neurology Authors: Tags: Alzheimer's disease, Corticobasal degeneration, Vascular dementia Case Source Type: research
Conclusions: Addition of a single test of median and ulnar sensory latency, the median and radial sensory latency or the inching method, in routine protocol will improve the sensitivity for the diagnosis of CTS in all patients.
Source: Neurology India - Category: Neurology Authors: Source Type: research
ConclusionThe results of this prospective study showed that the annualized incidence of CTS in our population of cashier was 2.0%; 40% of the new CTS cases had comorbidities.
Source: International Archives of Occupational and Environmental Health - Category: Occupational Health Source Type: research
Conclusions: Electrodiagnostic results showed both demyelinating injury and axonal damage in diabetes mellitus, HT, and RA patients with CTS, in these patients during treatment for CTS. Early treatment planning should include the risk factor diseases.
Source: Journal of Clinical Neurophysiology - Category: Neurology Tags: Original Research Source Type: research
Conclusions: Median nerve US is nearly as sensitive as EDx testing for the diagnosis of CTS. US may also have added value in detecting CTS in a select number of patients where EDx studies remain normal. Large prospective trials are needed to examine this question.Disclosure: Dr. Billakota has nothing to disclose. Dr. Hobson-Webb has received personal compensation for activities with Genzyme and Sanofi for speaking. Dr. Hobson-Webb holds stock and/or stock options in Aerpio Therapeutics. Dr. Hobson-Webb has received research support from Valerion Therapuetics and C
Source: Neurology - Category: Neurology Authors: Tags: MRI and Ultrasonography Studies in Peripheral Neuropathies Source Type: research
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