Improving motor development in infancy with iron supplementation

Study design Design: Four-group factorial, individually randomised placebo-controlled trial. Allocation: Allocation concealed: randomisation was undertaken by a remote statistician. Pregnant women were assigned to iron and folic acid (active) or folic acid alone. Their newborns were allocated to iron or a placebo control. Blinding: Supplements were delivered in identical dark bottles. Mothers and assessors were blinded. Study question Setting: Hebei, China. A community-based study randomising pregnant woman between June 2009 and December 2011and their babies between December 2009 and June 2011. Patients: 1482 infants of 2371 women who had been randomised to iron supplementation or placebo during pregnancy, and whose cord ferritin <35 mg/L. Included babies were of singleton pregnancies enrolled <20 weeks gestation. Intervention: 752 infants received 1 mg/kg iron and 730 placebo between 6 weeks and 9 months of age. Outcomes: Gross motor development was assessed using the Peabody Developmental Motor Scale Second Edition. Secondary outcomes were...
Source: Archives of Disease in Childhood - Education and Practice - Category: Pediatrics Authors: Tags: Clinical trials (epidemiology), Picket, Drugs: CNS (not psychiatric), Malnutrition, Pregnancy, Reproductive medicine, Developmental paediatrics STRUCTURED ABSTRACTS OF SENTINEL ARTICLES: Picket Source Type: research