NIAID-supported study examines vulnerability of gonorrhea to older antibiotic drug

(NIH/National Institute of Allergy and Infectious Diseases) A new clinical research study seeks to determine whether a rapid molecular diagnostic test can reliably identify gonorrhea infections that may be treated with a single dose of an older antibiotic, ciprofloxacin. The study will enroll up to 381 men and women diagnosed with untreated Neisseria gonorrhoeae. It is sponsored by the National Institute of Allergy and Infectious Diseases and is being conducted by the NIAID-funded Sexually Transmitted Infections Clinical Trials Group at four sites.
Source: EurekAlert! - Infectious and Emerging Diseases - Category: Infectious Diseases Source Type: news

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The Internet of Things is driving incredible innovation in healthcare. “Almost any new innovative medical device is currently designed as a part of broader interconnected system,” Rami Muleys, head of application security business development at Positive Technologies, told MD+DI. “The main value of IoT is the convergence between different systems and the ability to exchange data between every device – from an insulin pump to a hospital bed.” Healthcare is consequently “a constantly changing landscape, especially sinc...
Source: MDDI - Category: Medical Devices Authors: Tags: Business Source Type: news
Publication date: Available online 29 November 2018Source: Molecular and Cellular ProbesAuthor(s): Malik Siddique Mahmood, Muhammad Asad Ullah, Hina Batool, Sana Batool, Naeem Mehmood AshrafAbstractGonorrheal infections are the second most prevalent sexually transmitted diseases STDs in the USA populations after Chlamydia. These infections have now become an urgent problem to address because Neisseria gonorrhoeae is capable of developing resistance to multiple antibiotic classes. Infection with these antibiotic-resistant strains has become the major public health concern. Although extensive researches are ongoing to contro...
Source: Molecular and Cellular Probes - Category: Molecular Biology Source Type: research
We believe this to be the first report of coexisting polymerase chain reaction (PCR)-confirmed primary genital and ocular syphilis in a patient with penicillin allergy treated with doxycycline. The case examines the use of nonpenicillin and corticosteroid treatment of ocular syphilis and highlights the risk of eye involvement early in the disease process.
Source: Sexually Transmitted Diseases - Category: Sexual Medicine Tags: Notes Source Type: research
UCLA-led research finds that internet search terms and tweets related to sexual risk behaviors can predict when and where syphilis trends will occur.Two studies from the UCLA-based University of California Institute for Prediction Technology, in collaboration with the Centers for Disease Control and Prevention, or CDC, found an association between certain risk-related terms that Google and Twitter users researched or tweeted about and subsequent syphilis trends that were reported to the CDC. The researchers were able to pinpoint these cases at state or county levels, depending on the platform used.“Many of the most s...
Source: UCLA Newsroom: Health Sciences - Category: Universities & Medical Training Source Type: news
The National Institute of Allergy and Infectious Diseases has invented three chlamydial vaccine technologies, which have shown promising preclinical efficacy. Chlamydia trachomatis infection is the most common sexually transmitted bacterial infection. If left untreated, chlamydia infection can lead to pelvic inflammatory disease and infertility. Chlamydia is also the leading cause of preventable blindness in the world. Despite increased surveillance, prevalence continues to increase, and the need to develop an effective chlamydial vaccine remains.Technologies: 1. A plasmid-deficient Chlamydia trachomatis strain which was s...
Source: NIH OTT Licensing Opportunities - Category: Research Authors: Source Type: research
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Source: Health News from Medical News Today - Category: Consumer Health News Tags: Women's Health / Gynecology Source Type: news
National institute of allergy and infectious diseases workshop report: "Chlamydia vaccines: the way forward". Vaccine. 2017 Oct 30;: Authors: Zhong G, Brunham RC, de la Maza LM, Darville T, Deal C Abstract Chlamydia trachomatis (Ct), an intracellular pathogen, is the most common bacterial sexually transmitted infection. In addition to acute cervicitis and urethritis, Ct can lead to serious sequelae of significant public health burden including pelvic inflammatory disease (PID) and infertility. Ct control efforts have not resulted in desired outcomes such as reduced incidence and reinfection,...
Source: Vaccine - Category: Allergy & Immunology Authors: Tags: Vaccine Source Type: research
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Source: AllAfrica News: HIV-Aids and STDs - Category: Infectious Diseases Source Type: news
Researchers at Houston’s Baylor College of Medicine last week began Phase 2 clinical trials for a Zika vaccine that is expected to have results as early as the end of this year.  Andrew Pekosz, a professor of microbiology and immunology at Johns Hopkins University’s Bloomberg School of Public Health, praised the vaccine’s potential to prevent disease, as well as how quickly clinical trials have taken place.  “It’s really been a light-speed endeavor,” Pekosz, who was not involved in the vaccine’s testing or development at the National Institute for Allergy and In...
Source: Science - The Huffington Post - Category: Science Source Type: news
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Source: Health News from Medical News Today - Category: Consumer Health News Tags: Women's Health / Gynecology Source Type: news
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