Clinical evidence of variable proton biological effectiveness in pediatric patients treated for ependymoma
A constant relative biological effectiveness (RBE) is used for clinical proton therapy; however, experimental evidence indicates that RBE can vary. We analyzed pediatric ependymoma patients who received proton therapy to determine if areas of normal tissue damage indicated by post-treatment image changes were associated with increased biological dose effectiveness.
Source: Radiotherapy and Oncology - Category: Radiology Authors: Christopher R. Peeler, Dragan Mirkovic, Uwe Titt, Pierre Blanchard, Jillian R. Gunther, Anita Mahajan, Radhe Mohan, David R. Grosshans Tags: Original article Source Type: research