The effect of anatomical changes on pencil beam scanned proton dose distributions for cranial and extra cranial tumors

A retrospective analysis of the PSI adaptive planning strategy has been performed. Out of a cohort of 730 patients treated with PBS proton therapy, 244 (33.5%) had control CT ’s to monitor anatomical changes. Of these, 40 patients (5.5%) required re-planning. Retrospective re-calculation of the nominal plan on re-planning CT’s indicated that 88% of analyzed OARs were within 5% of the nominal planned dose and 87%/90% of analyzed PTV/CTV’s within 5%.

http://www.redjournal.org/article/S0360-3016(16)33436-8/fulltext?rss=yes

Source: International Journal of Radiation Oncology * Biology * Physics - November 15, 2016 Category: Radiology Authors: Lorenzo Placidi, Alessandra Bolsi, Antony J. Lomax, Ralf A. Schneider, Robert Malyapa, Damien C. Weber, Francesca Albertini Tags: Clinical Investigation Source Type: research