Acute kidney injury: Role of platelet activation and NETs in renal IRI

Nature Reviews Nephrology 12, 715 (2016). doi:10.1038/nrneph.2016.153 Author: Ellen F. Carney Platelet activation and the formation of neutrophil extracellular traps (NETs) contribute to renal ischaemia–reperfusion injury (IRI), say researchers. Jansen et al. show that in mice, renal IRI led to activation of platelets in the proximity of necrotic cell casts. The antiplatelet agent clopidogrel
Source: Nature Reviews Nephrology - Category: Urology & Nephrology Authors: Tags: Research Highlight Source Type: research