Acute kidney injury: Loss of PKC- ɛ protects against IRI

Nature Reviews Nephrology 12, 714 (2016). doi:10.1038/nrneph.2016.162 Author: Andrea Aguilar Sudden, temporary interruption of renal blood flow induces ischaemia–reperfusion injury (IRI), a major cause of acute renal failure. A new study conducted by Grazyna Nowak and colleagues shows that deletion of protein kinase C-ɛ (PKC-ɛ) prevents IRI-induced changes in mitochondrial function, kidney morphology and renal
Source: Nature Reviews Nephrology - Category: Urology & Nephrology Authors: Tags: Research Highlight Source Type: research