The 9 Sneaky Things That Are Causing Your Knee Pain

SPECIAL FROM Next Avenue Whether it came on suddenly when you were playing tennis or more gradually over many years, knee pain can keep you from doing even the most basic of activities. At the very least, it can limit your ability to move as easily or quickly, or sit in one place for an extended time.   Arthritis is the most common cause of knee pain for older adults, said Dr. Julie Switzer, an orthopedic surgeon at Regions Hospital in St. Paul, Minn. Arthritis comes in three main forms, she said: osteoarthritis, inflammatory arthritis and post-traumatic arthritis. We’ll examine these types, as well as other causes of knee pain, below. The others include Lyme arthritis, torn cartilage or ligament, tendinitis, bursitis, gout and spontaneous osteonecrosis of the knee. Then, we’ll offer some treatment options. Osteoarthritis Osteoarthritis, also known as degenerative joint disease, is the most common form of arthritis. It occurs when the cartilage, a rubbery material that covers the end of a bone, breaks down and may eventually wear away. The biomechanics of your knee have changed as a result of that injury. That exquisite, nearly frictionless movement has changed. — Dr. Julie Switzer, orthopedic surgeon “A lot of those patients will have morning stiffness — they’ll have what I call ‘movie theater knee,’” said Dr. Alan Reznik, an orthopedic surgeon in New Haven, Conn., and a spokesman for the American Academy of Ortho...
Source: Healthy Living - The Huffington Post - Category: Consumer Health News Source Type: news

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Authors: Silva MAFS, Dechichi P, Limirio PHJO Abstract Childhood obesity is a considerable worldwide health problem and a major risk factor for several chronic diseases. Fat rich diets result in altered serum levels of lipids, cytokines and hormonal factors, which influence skeletal acquisition and promote microstructural and mechanical behavior changes in bone, especially to bone quality and quantity. However, the possible longterm implications of high-fat diets in childhood are controversial. Despite not fully understood, multiple signaling pathways which support bone tissue homeostasis are altered under hyperlip...
Source: Pediatric Endocrinology Reviews - Category: Endocrinology Tags: Pediatr Endocrinol Rev Source Type: research
Authors: Scheffer-Rath ME, Boot AM Abstract Vitamin D is important for skeletal growth, bone mineralization and dental health. Vitamin D deficiency is reported in many countries, may have several causes and can cause rickets in children. A guideline with recommendations of vitamin D supplementation to prevent nutritional rickets was published recently. The vitamin D receptor is present in many cells of the body including cells of the immune system. Many studies have been published on associations between vitamin D deficiency and extra skeletal effects, mainly without proof of causality in intervention studies. This...
Source: Pediatric Endocrinology Reviews - Category: Endocrinology Tags: Pediatr Endocrinol Rev Source Type: research
Publication date: 5 December 2020Source: Journal of Ethnopharmacology, Volume 263Author(s): Xiaoning Chen, Ravindran Kalathil Veena, Haridas Ramya, Kainoor Krishnankutty Janardhanan, Varughese George
Source: Journal of Ethnopharmacology - Category: Drugs & Pharmacology Source Type: research
Publication date: Available online 12 August 2020Source: Current Therapeutic ResearchAuthor(s): D.D. Gladman, A.M. Orbai, J. Gomez-Reino, S. Chang-Douglass, E. Leoncini, H.E. Burton, K.S. Kanik, A.B. Romero, J.C. Cappelleri, M-A. Hsu
Source: Current Therapeutic Research - Category: Drugs & Pharmacology Source Type: research
To better understand and interpret the trends in cutaneous research, we carried out a network analysis of all the titles of the submitted abstracts of the annual meetings of the European Society of Dermatological Research (ESDR), including the International Investigative Dermatology (IID) meetings between 2010 and 2019. Network analysis is a data science tool to process, analyze, and visualize big sets of data. As expected, psoriasis was the frontrunner in each of the annual meetings, followed by dermatitis and melanoma.
Source: Journal of Investigative Dermatology - Category: Dermatology Authors: Tags: The ESDR in Numbers Source Type: research
ConclusionsNo difference between the LSTR and pulpectomy approaches could be confirmed by meta-analyses. The quality of evidence according to the GRADE scheme ranged from moderate to very low.Clinical relevanceThe present meta-analyses could not demonstrate the superiority of one treatment over the other.
Source: Clinical Oral Investigations - Category: Dentistry Source Type: research
Authors: Plunk EC, Richards SM Abstract The epigenome of an individual can be altered by endogenous hormones, environment, age, diet, and exposure to endocrine disrupting chemicals (EDCs), and the effects of these modifications can be seen across generations. Epigenetic modifications to the genome can alter the phenotype of the individual without altering the DNA sequence itself. Epigenetic modifications include DNA methylation, histone modification, and aberrant microRNA (miRNA) expression; they begin during germ cell development and embryogenesis and continue until death. Hormone modulation occurs during the agei...
Source: International Journal of Endocrinology - Category: Endocrinology Tags: Int J Endocrinol Source Type: research
Authors: Antinozzi C, Sgrò P, Di Luigi L Abstract Among metabolic diseases, carbohydrate metabolism disorders are the most widespread. The most common glucose pathological conditions are acquired and may increase the risk of type 2 diabetes, obesity, heart diseases, stroke, and kidney insufficiency. Phosphodiesterase type 5 inhibitors (PDE5i) have long been used as an effective therapeutic option for the treatment of erectile dysfunction (ED). Different studies have demonstrated that PDE5i, by sensitizing insulin target tissues to insulin, play an important role in controlling the action of insulin and gluco...
Source: International Journal of Endocrinology - Category: Endocrinology Tags: Int J Endocrinol Source Type: research
Authors: Vibhatavata P, Pisarnturakit P, Boonsripitayanon M, Pithuksurachai P, Plengvidhya N, Sirinvaravong S Abstract Postoperative hypoparathyroidism is a common complication of total or completion thyroidectomy. The association between preoperative vitamin D deficiency (VDD) and the development of more severe postoperative hypocalcemia is still unclear. Objectives. To evaluate the effect of preoperative VDD on severity of hypocalcemia in patients with hypoparathyroidism following thyroidectomy. Methods. Patients who developed acute hypoparathyroidism after total or completion thyroidectomy, defined as postoperat...
Source: International Journal of Endocrinology - Category: Endocrinology Tags: Int J Endocrinol Source Type: research
CONCLUSIONS: Prescribing pattern analysis showed the highest responses and remission rates with tocilizumab and TNF-α inhibitors. The main reasons for withdrawal were lack of response and adverse effects. Further research is needed to improve pharmacological RA management in real-life settings. PMID: 32767346 [PubMed - in process]
Source: European Review for Medical and Pharmacological Sciences - Category: Drugs & Pharmacology Tags: Eur Rev Med Pharmacol Sci Source Type: research
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