First time flu infection may affect lifetime immunity
Conclusion This modelling study shows how the strains of influenza A – "bird flu" – circulating when a person is born give them lifelong protection against new subtypes with the same H protein groups. The researchers call this immune imprinting. This may help to explain the high severity and mortality rate seen among certain groups. For example, the massive flu pandemic of 1918 was an H1N1 strain. This had a very high fatality rate among young adults, which the researchers consider may have been because when they were born (between 1880 and 1900), H3 was the dominant strain. Therefore they had no protection when encountering H1. However, elderly adults of the same generation did have protection when H3 peaked in 1968. These observations, however, aren't really too unexpected. It's already well known that the flu virus has many different strains; which is why people catch flu several times in their life, and why it's difficult to say the flu vaccine will definitely stop you catching flu (vaccines only cover the strain expected to be circulating that season). We also know that exposure to a specific virus gives us protection against the same if we encounter it again. So in that sense this isn't really "news" as such. Nevertheless, as the researchers say, their findings could help in planning for future flu outbreaks, in knowing which age groups may be most at risk. Though these are only modelling estimates so it's difficult to give certain answer...
Conclusions: Total Sequential Organ Failure Assessment may be used to predict severe maternal outcome in obstetric populations admitted to ICU. The Acute Physiology and Chronic Health Evaluation II may be applied to predict severe maternal outcome in hemorrhagic complications. We do not recommend Acute Physiology and Chronic Health Evaluation IV and Simplified Acute Physiology Score III for the prediction of severe maternal outcome.
Authors: Braga M, Moleiro ML, Guedes-Martins L Abstract The ductus venosus is a vascular shunt situated within the fetal liver parenchyma connecting the umbilical vein to the inferior vena cava. This vessel acts as a bypass of the liver microcirculation and plays a critical role in the fetal circulation. The ductus venosus allows oxygenated and nutrient-rich venous blood to flow from the placenta to the myocardium and brain. Increased impedance to flow in the fetal ductus venosus is associated with fetal aneuploidies, cardiac defects and other adverse pregnancy outcomes. This review serves to improve our understand...
Lately, it’s felt like there’s a new food recall each week, striking everything from romaine lettuce to Ritz crackers. And a new report from the non-partisan Public Interest Research Group (PIRG) says that phenomenon isn’t in your head: Food recalls are actually getting more common. The total number of food recalls in the U.S. increased by 10% between 2013 and 2018, hitting a peak of 905 in 2016, according to the report. Class I recalls — those based on a “reasonable probability” that contaminated food could cause health problems — of meat and poultry rose by 83% during this time p...
The disease spread within ultra-Orthodox Jewish communities where vaccination rates are low and some are suspicious of government health workers.
A new study concludes that some of the species of bacteria in our airways, called the respiratory microbiome, can protect us against the influenza virus.
Amie J. Eisfeld, David J. Gasper, M. Suresh, Yoshihiro Kawaoka
Life in limbo: Fertility clinics, couples struggle with what to do with leftover embryos from pregnancy attempts
CONCLUSIONS: Self-administration of misoprostol to induce pregnancy termination after 24 weeks' gestation contributes to preterm births and perinatal morbidity and mortality. The findings of this study show that there is a need to educate women on the perinatal and maternal risks associated with self-induced pregnancy termination at a late stage of gestation, availability of safe options for pregnancy termination, and contraceptive use and adherence. Healthcare workers need to be sensitive to the possibility that cases of apparent spontaneous preterm labour or birth may have been self-induced. PMID: 30645966 [PubMed - in process]
(MedPage Today) -- Also, understanding OPPS rules
Conclusions: We found a significant overlap between the aortic elastic properties in women with a history of preeclampsia and those with a previous HELLP syndrome, suggesting a common pathophysiologic pathway. However, women who experienced HELLP syndrome showed a higher blood pressure than other cases and controls, probably determining larger aortas. In addition, VAC was more altered in the HELLP group than in the others because of a higher Ea and a lower Ees.
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