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PRECISION: Celecoxib Similar to Ibuprofen, Naproxen for CV Risk PRECISION: Celecoxib Similar to Ibuprofen, Naproxen for CV Risk

Celecoxib hit its noninferiority CV mark against ibuprofen and naproxen in arthritis patients at increased CVD risk, but not all are convinced.Heartwire from Medscape
Source: Medscape Medical News Headlines - Category: Consumer Health News Tags: Cardiology News Source Type: news

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(Reuters) - A U.S. appeals court on Tuesday upheld a ruling that invalidated a crucial Johnson&Johnson patent on its blockbuster rheumatoid arthritis drug Remicade, limiting J&J ’s ability to seek damages from Pfizer Inc over its launch of a lower-cost version of the drug.
Source: Reuters: Health - Category: Consumer Health News Tags: healthNews Source Type: news
In January, 2018, Academic Press published my bookPrecision Medicine and the Reinvention of Human Disease. This book has an excellent " look inside " at itsGoogle book site, which includes the Table of Contents. In addition, I thought it might be helpful to see the topics listed in the Book's index. Note that page numbers followed by f indicate figures, t indicate tables, and ge indicate glossary terms.AAbandonware, 270, 310geAb initio, 34, 48ge, 108geABL (abelson leukemia) gene, 28, 58ge, 95 –97Absidia corymbifera, 218Acanthameoba, 213Acanthosis nigricans, 144geAchondroplasia, 74, 143ge, 354geAcne, 54ge, 1...
Source: Specified Life - Category: Information Technology Tags: index jules berman jules j berman precision medicine Source Type: blogs
ARTHRITIS pain affects about 10 million people in the UK. The condition can make exercising difficult - here ’s seven common mistakes you could be making.
Source: Daily Express - Health - Category: Consumer Health News Source Type: news
Are adults with arthritis receiving adequate counseling from their health care providers for exercise? What are the barriers, and how can improvements in counseling be facilitated?Morbidity &Mortality Weekly Report
Source: Medscape Today Headlines - Category: Consumer Health News Tags: Rheumatology Journal Article Source Type: news
ConclusionsHO-1/BVD/CO pathway activation provides anti-nociceptive and anti-inflammatory effects on the zymosan-induced TMJ hypernociception in rats.
Source: Inflammation Research - Category: Research Source Type: research
AbstractPost-traumatic arthritis (PTA) is characterized by the deterioration of articular cartilage temporally associated with an articular injury. With a paucity of literature comparing joint preservation techniques, we performed a systematic review of the literature intending to describe and summarize the results of ankle distraction arthroplasty as it compares with studies on tibio-talar microfracture, allograft, and autograft for ankle joint preservation in the post-traumatic population under 50  years of age. Research databases were searched and abstracts screened for relevance on our topic of interest. Abstracts...
Source: Strategies in Trauma and Limb Reconstruction - Category: Orthopaedics Source Type: research
Musculoskeletal disorders present major clinical and health economic challenges in the UK today. Musculoskeletal symptoms are among the most common causes of visits to general practitioners. Many people with chronic symptoms find their lifestyles considerably hampered, and these conditions are a major cause of lost work days. There are many different types of rheumatologic disorder, ranging from very common, chronically painful soft tissue conditions such as fibromyalgia, through osteoarthritis and inflammatory arthritis to the rarer but potentially life-threatening autoimmune conditions such as lupus erythematosus.
Source: Medicine - Category: Internal Medicine Authors: Tags: Introduction Source Type: research
Sometimes the old-fashioned, simple solution is more than sufficient for the task at hand. In today's open access review paper, researchers discuss the delivery and targeting of gene therapies to arthritic joint tissue via the simple expedient of injecting the therapeutic into the joint - the most modern of medical treatments married to a 150-year-old technology. And why not? The alternatives for targeting a therapy to a specific tissue are numerous, but all quite complicated and expensive: magnetic fields to guide metallic nanoparticles attached to the therapeutic; using seeker proteins that preferentially match the surfa...
Source: Fight Aging! - Category: Research Authors: Tags: Medicine, Biotech, Research Source Type: blogs
ARTHRITIS pain affects about 10 million people in the UK. The condition can make exercising difficult - here ’s seven common mistakes you could be making.
Source: Daily Express - Health - Category: Consumer Health News Source Type: news
Recentdata suggest that the lectin-like oxidized low-density lipoprotein (ox-LDL) receptor-1 (LOX-1)/ox-LDL system may be involved in the pathogenesis of arthritis. We aimed to demonstrate the roles of the LOX-1/ox-LDL system in arthritis development by using LOX-1 knockout (KO) mice. Arthritis was induced in the right knees of C57Bl/6 wild-type (WT) and LOX-1 KO mice via zymosan injection. Saline was injected in the left knees. Arthritis development was evaluated using inflammatory cell infiltration, synovial hyperplasia, and cartilage degeneration scores at 1, 3, and 7 days after administration. LOX-1, ox-LDL, and matrix...
Source: European Journal of Histochemistry - Category: Biomedical Science Source Type: research
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